[HTML][HTML] Conjunctival melanoma: New insights in tumour genetics and immunology, leading to new therapeutic options

NJ Brouwer, RM Verdijk, S Heegaard… - Progress in Retinal and …, 2022 - Elsevier
Recent developments in oncology have led to a better molecular and cellular understanding
of cancer, and the introduction of novel therapies. Conjunctival melanoma (CoM) is a rare …

Conjunctival melanoma-epidemiological trends and features

S Kaštelan, A Gverović Antunica… - Pathology & Oncology …, 2018 - Springer
Conjunctival melanoma is a rare but sight and life threatening malignancy. It accounts for
2%–5% of all ocular tumours and 5%–7% of all ocular melanomas with an incidence of 0.2 …

m6A modification suppresses ocular melanoma through modulating HINT2 mRNA translation

R Jia, P Chai, S Wang, B Sun, Y Xu, Y Yang, S Ge… - Molecular cancer, 2019 - Springer
Background Dynamic N 6-methyladenosine (m 6 A) RNA modification generated and
erased by N 6-methyltransferases and demethylases regulates gene expression, alternative …

BRAF mutations in conjunctival melanoma: investigation of incidence, clinicopathological features, prognosis and paired premalignant lesions

AC Larsen, C Dahl, CM Dahmcke… - Acta …, 2016 - Wiley Online Library
Purpose To investigate incidence, clinicopathological features and prognosis of BRAF‐
mutated conjunctival melanoma in Denmark. Furthermore, to determine BRAF mutations in …

Adopting low-shot deep learning for the detection of conjunctival melanoma using ocular surface images

TK Yoo, JY Choi, HK Kim, IH Ryu, JK Kim - Computer Methods and …, 2021 - Elsevier
Abstract Background and Objective The purpose of the present study was to investigate low-
shot deep learning models applied to conjunctival melanoma detection using a small …

Checkpoint inhibition immunotherapy for advanced local and systemic conjunctival melanoma: a clinical case series

PT Finger, AC Pavlick - Journal for ImmunoTherapy of Cancer, 2019 - Springer
Background Herein, we describe the use of systemic immunotherapy for both locally
advanced and metastatic conjunctival melanoma. Current treatments for advanced …

Conjunctival melanoma: current treatments and future options

JM Grimes, NV Shah, FH Samie, RD Carvajal… - American Journal of …, 2020 - Springer
Conjunctival melanoma is a rare tumor of the conjunctival epithelium with a heterogenous
clinical presentation and a propensity for regional and distant metastatic spread. Guidelines …

TLD1433 photosensitizer inhibits conjunctival melanoma cells in zebrafish ectopic and orthotopic tumour models

Q Chen, V Ramu, Y Aydar, A Groenewoud, XQ Zhou… - Cancers, 2020 - mdpi.com
The ruthenium-based photosensitizer (PS) TLD1433 has completed a phase I clinical trial
for photodynamic therapy (PDT) treatment of bladder cancer. Here, we investigated a …

Conjunctival malignant melanoma in D enmark: epidemiology, treatment and prognosis with special emphasis on tumorigenesis and genetic profile

AC Larsen - 2016 - Wiley Online Library
Conjunctival malignant melanoma is a rare disease associated with considerable mortality.
Most published data have been based on case reports or series of referred patients. In …

[HTML][HTML] Conjunctival melanoma: a clinical review and update

K Butt, R Hussain, SE Coupland, Y Krishna - Cancers, 2024 - mdpi.com
Simple Summary Conjunctival melanoma (Co-M) is a rare and aggressive eye surface
cancer. It is often misdiagnosed or overlooked, leading to late diagnosis. Co-M can cause …