The chemistry and biology of fungal meroterpenoids (2009–2019)

M Jiang, Z Wu, L Liu, S Chen - Organic & Biomolecular Chemistry, 2021 - pubs.rsc.org
Fungal meroterpenoids are secondary metabolites from mixed terpene-biosynthetic origins.
Their intriguing chemical structural diversification and complexity, potential bioactivities, and …

Absolute configuration determination by quantum mechanical calculation of chiroptical spectra: Basics and applications to fungal metabolites

S Superchi, P Scafato, M Gorecki… - Current medicinal …, 2018 - ingentaconnect.com
Background: Quantum mechanical simulations of chiroptical properties, such as electronic
circular dichroism (ECD), optical rotation (OR), and vibrational circular dichroism (VCD) …

Synthetic biology based construction of biological activity-related library of fungal decalin-containing diterpenoid pyrones

K Tsukada, S Shinki, A Kaneko, K Murakami… - Nature …, 2020 - nature.com
A synthetic biology method based on heterologous biosynthesis coupled with genome
mining is a promising approach for increasing the opportunities to rationally access natural …

Gene family expansions and contractions are associated with host range in plant pathogens of the genus Colletotrichum

R Baroncelli, DB Amby, A Zapparata, S Sarrocco… - BMC genomics, 2016 - Springer
Background Many species belonging to the genus Colletotrichum cause anthracnose
disease on a wide range of plant species. In addition to their economic impact, the genus …

Divergent synthesis of pyrone diterpenes via radical cross coupling

RR Merchant, KM Oberg, Y Lin… - Journal of the …, 2018 - ACS Publications
A divergent strategy for assembling pyrone diterpenes is presented. Capitalizing on the
unique stereo-and chemoselectivity features of radical-based chemistry, the core decalin of …

Chemistry of fungal meroterpenoid cyclases

L Barra, I Abe - Natural Product Reports, 2021 - pubs.rsc.org
Covering: up to July 2020 Fungal meroterpenoid cyclases are a recently discovered
emerging family of membrane-integrated, non-canonical terpene cyclases. They catalyze …

Enantioselective Divergent Syntheses of Diterpenoid Pyrones

Y Ji, Y Liu, W Guan, C Guo, H Jia… - Journal of the American …, 2024 - ACS Publications
Capitalizing a synergy between late-stage C (sp3)–H alkynylation and a series of transition
metal-catalyzed alkyne functionalization reactions, we reported herein enantioselective …

Diterpenes and their derivatives as potential anticancer agents

MT Islam - Phytotherapy Research, 2017 - Wiley Online Library
As therapeutic tools, diterpenes and their derivatives have gained much attention of the
medicinal scientists nowadays. It is due to their pledging and important biological activities …

The development of extracellular vesicle markers for the fungal phytopathogen Colletotrichum higginsianum

BD Rutter, TTH Chu, JF Dallery, KK Zajt… - Journal of …, 2022 - Wiley Online Library
Fungal phytopathogens secrete extracellular vesicles (EVs) associated with enzymes and
phytotoxic metabolites. While these vesicles are thought to promote infection, defining the …

Truncatenolide, a Bioactive Disubstituted Nonenolide Produced by Colletotrichum truncatum, the Causal Agent of Anthracnose of Soybean in Argentina: Fungal …

M Masi, S Castaldi, F Sautua, G Pescitelli… - Journal of Agricultural …, 2022 - ACS Publications
A bioactive disubstituted nonenolide, named truncatenolide, was produced by
Colletotrichum truncatum, which was collected from infected tissues of soybean showing …