An Update on Candida tropicalis Based on Basic and Clinical Approaches

DL Zuza-Alves, WP Silva-Rocha… - Frontiers in …, 2017 - frontiersin.org
Candida tropicalis has emerged as one of the most important Candida species. It has been
widely considered the second most virulent Candida species, only preceded by C. albicans …

Recent Advances in the Use of Galleria mellonella Model to Study Immune Responses against Human Pathogens

TC Pereira, PP De Barros, LRO Fugisaki, RD Rossoni… - Journal of Fungi, 2018 - mdpi.com
The use of invertebrates for in vivo studies in microbiology is well established in the scientific
community. Larvae of Galleria mellonella are a widely used model for studying …

What Do We Know about Candida auris? State of the Art, Knowledge Gaps, and Future Directions

V Garcia-Bustos, MD Cabanero-Navalon, A Ruiz-Saurí… - Microorganisms, 2021 - mdpi.com
Candida auris has unprecedently emerged as a multidrug resistant fungal pathogen,
considered a serious global threat due to its potential to cause nosocomial outbreaks and …

Immune Response of Galleria mellonella against Human Fungal Pathogens

N Trevijano-Contador, O Zaragoza - Journal of Fungi, 2018 - mdpi.com
In many aspects, the immune response against pathogens in insects is similar to the innate
immunity in mammals. This has caused a strong interest in the scientific community for the …

[HTML][HTML] Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms

P Van Dijck, J Sjollema, BPA Cammue, K Lagrou… - Microbial Cell, 2018 - ncbi.nlm.nih.gov
Unlike superficial fungal infections of the skin and nails, which are the most common fungal
diseases in humans, invasive fungal infections carry high morbidity and mortality …

Galleria mellonella as a model host for microbiological and toxin research

OL Champion, S Wagley, RW Titball - Virulence, 2016 - Taylor & Francis
Mammals are widely used by microbiologists as a model host species to study infectious
diseases of humans and domesticated livestock. These studies have been pivotal for our …

Galleria mellonella for the Evaluation of Antifungal Efficacy against Medically Important Fungi, a Narrative Review

S Jemel, J Guillot, K Kallel, F Botterel, E Dannaoui - Microorganisms, 2020 - mdpi.com
The treatment of invasive fungal infections remains challenging and the emergence of new
fungal pathogens as well as the development of resistance to the main antifungal drugs …

The Use of Galleria mellonella Larvae to Identify Novel Antimicrobial Agents against Fungal Species of Medical Interest

K Kavanagh, G Sheehan - Journal of Fungi, 2018 - mdpi.com
The immune system of insects and the innate immune response of mammals share many
similarities and, as a result, insects may be used to assess the virulence of fungal pathogens …

Antifungal Efficacy during Candida krusei Infection in Non-Conventional Models Correlates with the Yeast In Vitro Susceptibility Profile

L Scorzoni, MP de Lucas, AC Mesa-Arango… - PloS one, 2013 - journals.plos.org
The incidence of opportunistic fungal infections has increased in recent decades due to the
growing proportion of immunocompromised patients in our society. Candida krusei has …

From moths to caterpillars: Ideal conditions for Galleria mellonella rearing for in vivo microbiological studies

AL Jorjão, LD Oliveira, L Scorzoni… - Virulence, 2018 - Taylor & Francis
Galleria mellonella is a well-accepted insect model for the study of pathogen-host
interactions and antimicrobial compounds. The main advantages of this model include the …