The Pharmacological Activities of Crocus sativus L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents
M Butnariu, C Quispe, J Herrera-Bravo… - Oxidative medicine …, 2022 - Wiley Online Library
Crocus species are mainly distributed in North Africa, Southern and Central Europe, and
Western Asia, used in gardens and parks as ornamental plants, while Crocus sativus …
Western Asia, used in gardens and parks as ornamental plants, while Crocus sativus …
The vitamin D receptor as a potential target for the treatment of age-related neurodegenerative diseases such as Alzheimer's and Parkinson's diseases: A narrative …
W Lasoń, D Jantas, M Leśkiewicz, M Regulska… - Cells, 2023 - mdpi.com
The vitamin D receptor (VDR) belongs to the nuclear receptor superfamily of transcription
factors. The VDR is expressed in diverse brain regions and has been implicated in the …
factors. The VDR is expressed in diverse brain regions and has been implicated in the …
[HTML][HTML] Rosmarinic acid and its derivatives: Current insights on anticancer potential and other biomedical applications
Cancer is still the leading cause of death worldwide, burdening the global medical system.
Rosmarinic acid (RA) is among the first secondary metabolites discovered and it is a …
Rosmarinic acid (RA) is among the first secondary metabolites discovered and it is a …
Phenolic compounds as Nrf2 inhibitors: potential applications in cancer therapy
J Sharifi-Rad, V Seidel, M Izabela… - Cell Communication and …, 2023 - Springer
Cancer is a leading cause of death worldwide and involves an oxidative stress mechanism.
The transcription factor Nrf2 has a crucial role in cytoprotective response against oxidative …
The transcription factor Nrf2 has a crucial role in cytoprotective response against oxidative …
[HTML][HTML] Recent advances in the therapeutic potential of emodin for human health
J Sharifi-Rad, J Herrera-Bravo, S Kamiloglu… - Biomedicine & …, 2022 - Elsevier
Abstract Emodin (1, 3, 8-trihydroxy-6-methylanthraquinone) is a bioactive compound, a
natural anthraquinone aglycone, present mainly in herbaceous species of the families …
natural anthraquinone aglycone, present mainly in herbaceous species of the families …
Recent updates on anticancer mechanisms of polyphenols
In today's scenario, when cancer cases are increasing rapidly, anticancer herbal
compounds become imperative. Studies on the molecular mechanisms of action of …
compounds become imperative. Studies on the molecular mechanisms of action of …
Multi-target mechanisms of phytochemicals in Alzheimer's disease: Effects on oxidative stress, neuroinflammation and protein aggregation
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a tangle-shaped
accumulation of beta-amyloid peptide fragments and Tau protein in brain neurons. The …
accumulation of beta-amyloid peptide fragments and Tau protein in brain neurons. The …
The role of tumour necrosis factor in neuroinflammation associated with Parkinson's disease and targeted therapies
Neurodegenerative disorders Parkinson's disease is a progressive neurodegenerative
disorder associated with neuroinflammatory responses that lead to the neurodegeneration …
disorder associated with neuroinflammatory responses that lead to the neurodegeneration …
[HTML][HTML] Camellia sinensis: insights on its molecular mechanisms of action towards nutraceutical, anticancer potential and other therapeutic applications
The Camellia sinensis plant provides a wide diversity of black, green, oolong, yellow, brick
dark, and white tea. Tea is one of the majorly used beverages across the globe, succeeds …
dark, and white tea. Tea is one of the majorly used beverages across the globe, succeeds …
Τelomerase inhibitors and activators in aging and cancer: A systematic review
P Fragkiadaki, E Renieri… - Molecular …, 2022 - spandidos-publications.com
The main aim of the present systematic review was to summarize the most frequently used
telomerase regulators with an impact on aging and cancer that are referred to in in vitro and …
telomerase regulators with an impact on aging and cancer that are referred to in in vitro and …