Myocarditis in humans and in experimental animal models

P Błyszczuk - Frontiers in cardiovascular medicine, 2019 - frontiersin.org
Myocarditis is defined as an inflammation of the cardiac muscle. In humans, various
infectious and non-infectious triggers induce myocarditis with a broad spectrum of …

Ceramide and related molecules in viral infections

N Beckmann, KA Becker - International Journal of Molecular Sciences, 2021 - mdpi.com
Ceramide is a lipid messenger at the heart of sphingolipid metabolism. In concert with its
metabolizing enzymes, particularly sphingomyelinases, it has key roles in regulating the …

Autoimmunity in viral myocarditis

J Reddy, C Massilamany, I Buskiewicz… - Current opinion in …, 2013 - journals.lww.com
Autoimmunity in viral myocarditis : Current Opinion in Rheumatology Autoimmunity in viral
myocarditis : Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe …

The frequency of invariant natural killer T cells correlates with the severity of myocarditis

X Wang, M Li, Y Xie, Y Yu, G Liu, Y Yu, X Yang… - Viral …, 2014 - liebertpub.com
Invariant natural killer T cells (iNKT) perform different functions in different diseases. The
cells were reported to protect myocarditis. However, the detail relationships between iNKT …

Sphingosine 1-phosphate alleviates Coxsackievirus B3-induced myocarditis by increasing invariant natural killer T cells

X Wang, Y Yu, M Li, Y Yu, G Liu, Y Xie, Y Liu… - Experimental and …, 2017 - Elsevier
Abstract Sphingosine 1-phosphate (S1P), via binding to its specific receptors of S1PR1,
participates in the regulation of both innate and adaptive immunity. Recent reports have …

Role of T Cells in Viral and Immune-mediated Myocarditis

C Cheng, A Baritussio, AS Giordani… - Cardiology …, 2024 - mednexus.org
Myocarditis is characterized by inflammatory cell infiltration into the myocardium and a high
risk of deteriorating cardiac function with a heterogeneous etiology. Both viral-and myosin …

Mapping of a quantitative trait locus controlling susceptibility to Coxsackievirus B3-induced viral hepatitis

SA Wiltshire, J Marton, GA Leiva-Torres, SM Vidal - Genes & Immunity, 2015 - nature.com
The pathogenesis of coxsackieviral infection is a multifactorial process involving host
genetics, viral genetics and the environment in which they interact. We have used a mouse …

Genetic Regulation of NKT Cell Function

M Malagic - 2017 - scholarworks.uvm.edu
NKT cells are specialized T cells that play important roles in the host immune response to
bacteria and viruses. NKT cells produce a wide variety of cytokines and chemokines after …