Piperine: A review of its biological effects

IU Haq, M Imran, M Nadeem, T Tufail… - Phytotherapy …, 2021 - Wiley Online Library
Medicinal plants have been used for years as a source of food, spices, and, in traditional
medicine, as a remedy to numerous diseases. Piper nigrum, belonging to the family …

Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials

AK Tripathi, AK Ray, SK Mishra - Beni-Suef university journal of basic and …, 2022 - Springer
Background Piperine is a type of amide alkaloid that exhibits pleiotropic properties like
antioxidant, anticancer, anti-inflammatory, antihypertensive, hepatoprotective …

Capsaicin in metabolic syndrome

SK Panchal, E Bliss, L Brown - Nutrients, 2018 - mdpi.com
Capsaicin, the major active constituent of chilli, is an agonist on transient receptor potential
vanilloid channel 1 (TRPV1). TRPV1 is present on many metabolically active tissues …

Ellagic acid attenuates high-carbohydrate, high-fat diet-induced metabolic syndrome in rats

SK Panchal, L Ward, L Brown - European journal of nutrition, 2013 - Springer
Background Fruits and nuts may prevent or reverse common human health conditions such
as obesity, diabetes and hypertension; together, these conditions are referred to as …

Phytochemicals targeting Toll-like receptors 4 (TLR4) in inflammatory bowel disease

W Dai, L Long, X Wang, S Li, H Xu - Chinese medicine, 2022 - Springer
Inflammatory bowel disease (IBD) is a collective term for inflammatory diseases including
Crohn's disease and ulcerative colitis. Toll-like receptor 4 (TLR4) is thought to play a key …

Piperine suppresses cerebral ischemia–reperfusion-induced inflammation through the repression of COX-2, NOS-2, and NF-κB in middle cerebral artery occlusion rat …

K Vaibhav, P Shrivastava, H Javed, A Khan… - Molecular and cellular …, 2012 - Springer
The pathophysiological mechanisms leading to neuronal injury in middle cerebral artery
occlusion (MCAO) model of cerebral stroke are complex and multifactorial that form the …

Anti-inflammatory properties of culinary herbs and spices that ameliorate the effects of metabolic syndrome

A Jungbauer, S Medjakovic - Maturitas, 2012 - Elsevier
Obesity and metabolic syndrome are increasing global health problems. In addition to the
malnutrition of a sedentary lifestyle, high calorie intake leads to obesity with many negative …

Cardiovascular protective effect of black pepper (Piper nigrum L.) and its major bioactive constituent piperine

D Wang, L Zhang, J Huang, K Himabindu… - Trends in Food Science …, 2021 - Elsevier
Abstract Background Cardiovascular diseases (CVDs) are the leading cause of death
worldwide. Black pepper, the fruits of Piper nigrum L., is well known as “the king of spices” …

Therapeutic spectrum of piperine for clinical practice: a scoping review

SS Yadav, MK Singh, S Hussain… - Critical Reviews in …, 2023 - Taylor & Francis
Translation of traditional knowledge of herbs into a viable product for clinical use is still an
uphill task. Piperine, a pungent alkaloid molecule derived from Piper nigrum and Piper …

Asiatic acid alleviates hemodynamic and metabolic alterations via restoring eNOS/iNOS expression, oxidative stress, and inflammation in diet-induced metabolic …

P Pakdeechote, S Bunbupha, U Kukongviriyapan… - Nutrients, 2014 - mdpi.com
Asiatic acid is a triterpenoid isolated from Centella asiatica. The present study aimed to
investigate whether asiatic acid could lessen the metabolic, cardiovascular complications in …