Tumor metastasis and the lymphatic vasculature

JP Sleeman, W Thiele - International Journal of Cancer, 2009 - Wiley Online Library
Tumor‐associated lymphatic vessels act as a conduit by which disseminating tumor cells
access regional lymph nodes and form metastases there. Lymph node metastasis is of major …

[HTML][HTML] International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 3 …

C Magi-Galluzzi, AJ Evans, B Delahunt, JI Epstein… - Modern Pathology, 2011 - Elsevier
Abstract The International Society of Urological Pathology Consensus Conference on
Handling and Staging of Radical Prostatectomy Specimens in Boston made …

Tumor lymphangiogenesis and new drug development

LC Dieterich, M Detmar - Advanced drug delivery reviews, 2016 - Elsevier
Traditionally, tumor-associated lymphatic vessels have been regarded as passive by-
standers, serving simply as a drainage system for interstitial fluid generated within the tumor …

Lymphatic vessels in cancer metastasis: bridging the gaps

R Shayan, MG Achen, SA Stacker - Carcinogenesis, 2006 - academic.oup.com
Distant organ metastasis is the most important factor in determining patient survival in
cancer. This is thought to occur via the body's own systems for transporting fluid and cells …

Deep learning approach to predict lymph node metastasis directly from primary tumour histology in prostate cancer

F Wessels, M Schmitt, E Krieghoff‐Henning… - BJU …, 2021 - Wiley Online Library
Objective To develop a new digital biomarker based on the analysis of primary tumour tissue
by a convolutional neural network (CNN) to predict lymph node metastasis (LNM) in a cohort …

First international consensus on the methodology of lymphangiogenesis quantification in solid human tumours

I Van der Auwera, Y Cao, JC Tille, MS Pepper… - British journal of …, 2006 - nature.com
The lymphatic system is the primary pathway of metastasis for most human cancers. Recent
research efforts in studying lymphangiogenesis have suggested the existence of a …

Rapamycin, a specific inhibitor of the mammalian target of rapamycin, suppresses lymphangiogenesis and lymphatic metastasis

S Kobayashi, T Kishimoto, S Kamata, M Otsuka… - Cancer …, 2007 - Wiley Online Library
Tumor lymphangiogenesis is now known to play a causal role in lymph node metastasis,
and thus its inhibition would have great significance for the prevention of lymph node …

Mechanism of lymph node metastasis in prostate cancer

K Datta, M Muders, H Zhang, DJ Tindall - Future oncology, 2010 - Taylor & Francis
Detection of lymph node metastases indicates poor prognosis for prostate cancer patients.
Therefore, elucidation of the mechanism (s) of lymph node metastasis is important to …

Regulation of tumor invasion by interstitial fluid flow

AC Shieh, MA Swartz - Physical biology, 2011 - iopscience.iop.org
The importance of the tumor microenvironment in cancer progression is undisputed, yet the
significance of biophysical forces in the microenvironment remains poorly understood …

VEGF-C and VEGF-D expression is correlated with lymphatic vessel density and lymph node metastasis in oral squamous cell carcinoma: Implications for use as a …

T Sugiura, Y Inoue, R Matsuki… - International …, 2009 - spandidos-publications.com
The prognosis of patients with oral squamous cell carcinoma (SCC) is influenced by the
presence of lymph node metastasis. In this study, we analyzed the relationship between …