Lipid vesicle-based molecular robots

Z Peng, S Iwabuchi, K Izumi, S Takiguchi, M Yamaji… - Lab on a Chip, 2024 - pubs.rsc.org
A molecular robot, which is a system comprised of one or more molecular machines and
computers, can execute sophisticated tasks in many fields that span from nanomedicine to …

[HTML][HTML] Nanopore sensing and beyond: Electrochemical systems for optically-coupled single-entity studies, stimulus-responsive gating applications, and point-of-care …

J Reitemeier, J Metro, KX Fu - Sensors and Actuators Reports, 2024 - Elsevier
Nanopores play essential roles in biological processes, such as ion channels and pumps in
cellular membranes, and in technological applications such as DNA sequencing …

Understanding Electrophoresis and Electroosmosis in Nanopore Sensing with the Help of the Nanopore Electro-Osmotic Trap

C Wen, S Schmid, C Dekker - ACS nano, 2024 - ACS Publications
Nanopore technology is widely used for sequencing DNA, RNA, and peptides with single-
molecule resolution, for fingerprinting single proteins, and for detecting metabolites …

Controlling electroosmosis in nanopores without altering the nanopore sensing region

M Baldelli, G Di Muccio, A Sauciuc… - Advanced …, 2024 - Wiley Online Library
Nanopores are powerful tools for single‐molecule sensing of biomolecules and
nanoparticles. The signal coming from the molecule to be analyzed strongly depends on its …

Evidence of Cytolysin A nanopore incorporation in mammalian cells assessed by a graphical user interface

FLR Lucas, RK Finol-Urdaneta, T Van Thillo… - Nanoscale, 2023 - pubs.rsc.org
Technologies capable of assessing cellular metabolites with high precision and temporal
resolution are currently limited. Recent developments in the field of nanopore sensors allow …

Size-tunable Transmembrane Nanopores Assembled from Decomposable Molecular Templates

Z Su, T Chen, X Liu, X Kang - Biosensors and Bioelectronics, 2024 - Elsevier
Transmembrane nanopores, as key elements in molecular transport and single-molecule
sensors, are assembled naturally from multiple monomers in the presence of lipid bilayers …

A nanopore-based label-free CRISPR/Cas12a system for Portable and Ultrasensitive Detection of Zearalenone

Z Pei, Z Su, J Chen, W Li, D Wu, L Li, Y Wu, G Li - Analytica Chimica Acta, 2024 - Elsevier
Background Food safety has become a serious global concern. Therefore, there is a need
for effective detection technologies in this field. Currently, the development of effective on …

Hybrid lipid-block copolymer membranes enable stable reconstitution of a wide range of nanopores and robust sampling of serum

E Vreeker, F Grunewald, N van der Heide, SJ Marrink… - bioRxiv, 2024 - biorxiv.org
Biological nanopores are powerful tools for detecting biomolecules at the single-molecule
level, making them appealing as sensors for biological samples. However, the lipid …

Drug discovery for misfolding diseases using structure-based iterative learning

R Horne - 2024 - repository.cam.ac.uk
Computational methods such as machine learning hold the promise to reduce the costs and
the failure rates of conventional drug discovery pipelines. This issue is pressing for …

Machine learning assisted single-molecule sensing of per-and polyfluoroalkyl carboxylic acids: Quantification without standards

K Qiu, J Zuo, HS Li, W Tang, X Zhao, MY Cheng… - 2024 - researchsquare.com
Per-and polyfluoroalkyl carboxylic acids (PFCA) are of great concern due to their ubiquitous
presence in the environment. Despite a severe shortage of authentic standards, compared …