[HTML][HTML] Molecular mechanisms of stress granule assembly and disassembly

S Hofmann, N Kedersha, P Anderson… - Biochimica et Biophysica …, 2021 - Elsevier
Stress granules (SGs) are membrane-less ribonucleoprotein (RNP)-based cellular
compartments that form in the cytoplasm of a cell upon exposure to various environmental …

Intrinsically disordered proteins: critical components of the wetware

P Kulkarni, S Bhattacharya, S Achuthan… - Chemical …, 2022 - ACS Publications
Despite the wealth of knowledge gained about intrinsically disordered proteins (IDPs) since
their discovery, there are several aspects that remain unexplored and, hence, poorly …

Advances in targeting the WNT/β-catenin signaling pathway in cancer

A Chatterjee, S Paul, B Bisht, S Bhattacharya… - Drug Discovery …, 2022 - Elsevier
WNT/β-catenin signaling orchestrates various physiological processes, including embryonic
development, growth, tissue homeostasis, and regeneration. Abnormal WNT/β-catenin …

[HTML][HTML] Cellular control of viscosity counters changes in temperature and energy availability

LB Persson, VS Ambati, O Brandman - Cell, 2020 - cell.com
Cellular functioning requires the orchestration of thousands of molecular interactions in time
and space. Yet most molecules in a cell move by diffusion, which is sensitive to external …

Liquid biomolecular condensates and viral lifecycles: review and perspectives

TA Etibor, Y Yamauchi, MJ Amorim - Viruses, 2021 - mdpi.com
Viruses are highly dependent on the host they infect. Their dependence triggers processes
of virus–host co-adaptation, enabling viruses to explore host resources whilst escaping …

Yin and yang regulation of stress granules by Caprin-1

D Song, L Kuang, L Yang, L Wang… - Proceedings of the …, 2022 - National Acad Sciences
Stress granules (SGs) are cytoplasmic biomolecular condensates containing proteins and
RNAs in response to stress. Ras-GTPase–activating protein binding protein 1 (G3BP1) is a …

The intrinsically disorderly story of Ki-67

L Remnant, NY Kochanova, C Reid… - Open …, 2021 - royalsocietypublishing.org
Ki-67 is one of the most famous marker proteins used by histologists to identify proliferating
cells. Indeed, over 30 000 articles referring to Ki-67 are listed on PubMed. Here, we review …

[图书][B] RNA, the epicenter of genetic information

J Mattick, P Amaral - 2023 - library.oapen.org
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Multiplex-GAM: genome-wide identification of chromatin contacts yields insights overlooked by Hi-C

RA Beagrie, CJ Thieme, C Annunziatella, C Baugher… - Nature …, 2023 - nature.com
Technology for measuring 3D genome topology is increasingly important for studying gene
regulation, for genome assembly and for mapping of genome rearrangements. Hi-C and …

Implementation of residue-level coarse-grained models in GENESIS for large-scale molecular dynamics simulations

C Tan, J Jung, C Kobayashi, DUL Torre… - PLOS Computational …, 2022 - journals.plos.org
Residue-level coarse-grained (CG) models have become one of the most popular tools in
biomolecular simulations in the trade-off between modeling accuracy and computational …