Pharmacological Profile of Xanthohumol, a Prenylated Flavonoid from Hops (Humulus lupulus)
M Liu, PE Hansen, G Wang, L Qiu, J Dong, H Yin… - Molecules, 2015 - mdpi.com
The female inflorescences of hops (Humulus lupulus L.), a well-known bittering agent used
in the brewing industry, have long been used in traditional medicines. Xanthohumol (XN) is …
in the brewing industry, have long been used in traditional medicines. Xanthohumol (XN) is …
An update on antitumor activity of naturally occurring chalcones
EH Zhang, RF Wang, SZ Guo… - … Based Complementary and …, 2013 - Wiley Online Library
Chalcones, which have characteristic 1, 3‐diaryl‐2‐propen‐1‐one skeleton, are mainly
produced in roots, rhizomes, heartwood, leaves, and seeds of genera Angelica, Sophora …
produced in roots, rhizomes, heartwood, leaves, and seeds of genera Angelica, Sophora …
Cancer chemoprevention revisited: cytochrome P450 family 1B1 as a target in the tumor and the microenvironment
Cancer chemoprevention is the use of synthetic, natural or biological agents to prevent or
delay the development or progression of malignancies. Intriguingly, many phytochemicals …
delay the development or progression of malignancies. Intriguingly, many phytochemicals …
Angiogenesis and inflammation signaling are targets of beer polyphenols on vascular cells
R Negrao, R Costa, D Duarte… - Journal of cellular …, 2010 - Wiley Online Library
Emerging evidence indicates that chronic inflammation and oxidative stress cluster together
with angiogenic imbalance in a wide range of pathologies. In general, natural polyphenols …
with angiogenic imbalance in a wide range of pathologies. In general, natural polyphenols …
[HTML][HTML] Hop derived flavonoid xanthohumol inhibits endothelial cell functions via AMPK activation
C Gallo, K Dallaglio, B Bassani, T Rossi, A Rossello… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Angiogenesis, a process characterized by the formation of new blood vessels from pre-
existing ones, is a crucial step in tumor growth and dissemination. Recently, increased …
existing ones, is a crucial step in tumor growth and dissemination. Recently, increased …
Xanthohumol Blocks Proliferation and Migration of Vascular Smooth Muscle Cells in Vitro and Reduces Neointima Formation in Vivo
R Liu, EH Heiss, D Schachner, B Jiang… - Journal of natural …, 2017 - ACS Publications
Xanthohumol (1) is a principal prenylated chalcone found in hops. The aim of this study was
to examine its influence on platelet-derived growth factor (PDGF)-BB-triggered vascular …
to examine its influence on platelet-derived growth factor (PDGF)-BB-triggered vascular …
Novel nitrogen-based chalcone analogs provoke substantial apoptosis in HER2-positive human breast cancer cells via JNK and ERK1/ERK2 signaling pathways
Natural chalcones possess antitumor properties and play a role as inducers of apoptosis,
antioxidants and cytotoxic compounds. We recently reported that novel nitrogen chalcone …
antioxidants and cytotoxic compounds. We recently reported that novel nitrogen chalcone …
Nutrigenetics, nutrigenomics and phenotypic outcomes of dietary low-dose alcohol consumption in the suppression and induction of cancer development: evidence …
F Caradonna, I Cruciata, C Luparello - Critical reviews in food …, 2022 - Taylor & Francis
It is known that the intake of alcoholic beverages may impair genetic and epigenetic
regulatory events with consequent crucial effects on cell phenotypes and that its association …
regulatory events with consequent crucial effects on cell phenotypes and that its association …
Isoxanthohumol modulates angiogenesis and inflammation via vascular endothelial growth factor receptor, tumor necrosis factor alpha and nuclear factor kappa B …
Angiogenesis and inflammation are becoming distinguished players in the pathogenesis of
many heterogeneous diseases, such as diabetes, cardiovascular disease, and cancer …
many heterogeneous diseases, such as diabetes, cardiovascular disease, and cancer …
Poly (ethylmethacrylate-co-diethylaminoethyl acrylate) coating improves endothelial re-population, bio-mechanical and anti-thrombogenic properties of decellularized …
E López-Ruiz, S Venkateswaran, M Perán… - Scientific Reports, 2017 - nature.com
Decellularized vascular scaffolds are promising materials for vessel replacements. However,
despite the natural origin of decellularized vessels, issues such as biomechanical …
despite the natural origin of decellularized vessels, issues such as biomechanical …