Atherosclerosis is a chronic inflammatory disease of the vascular system and is the leading
cause of cardiovascular diseases worldwide. Excessive generation of reactive oxygen …

A link between oxidative stress and hypertension has been firmly established in multiple
animal models of hypertension but remains elusive in humans. While initial studies focused …

Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of
molecules with oxidizing properties known as ROS. Despite those molecules being implied …

Abstract Calcium (Ca 2+) and reactive oxygen species (ROS) are versatile signaling
molecules coordinating physiological and pathophysiological processes. While channels …

Increased pulmonary vascular permeability due to endothelial cell (EC) barrier dysfunction
is a major pathological feature of acute respiratory distress syndrome/acute lung injury …

Although acute exposure of the heart to angiotensin (Ang II) produces physiological cardiac
hypertrophy and chronic exposure results in pathological hypertrophy, the signal …

Duchenne muscular dystrophy (DMD) is an X-linked muscle-wasting disease caused by the
loss of dystrophin. DMD is associated with muscle degeneration, necrosis, inflammation …

Production of reactive oxygen species (ROS) via the activity of respiratory burst oxidase
homologs (RBOHs) plays a vital role in multiple layers of the plant immune system, including …

The cellular formation of reactive oxygen species (ROS) represents an evolutionary ancient
antimicrobial defense system against microorganisms. The NADPH oxidases (NOX), which …

Many retinal diseases, such as diabetic retinopathy, glaucoma, and age-related macular
(AMD) degeneration, are associated with elevated reactive oxygen species (ROS) levels …