Interleukin 17 family cytokines: signaling mechanisms, biological activities, and therapeutic implications
L Monin, SL Gaffen - Cold Spring Harbor perspectives in …, 2018 - cshperspectives.cshlp.org
The cytokines of the interleukin 17 (IL-17) family play a central role in the control of
infections, especially extracellular fungi. Conversely, if unrestrained, these inflammatory …
infections, especially extracellular fungi. Conversely, if unrestrained, these inflammatory …
Selected cytokine pathways in rheumatoid arthritis
M Noack, P Miossec - Seminars in immunopathology, 2017 - Springer
Rheumatoid arthritis (RA) is a chronic inflammatory disease leading to joint destruction.
Cytokines play a key role in its pathogenesis. They contribute to the induction and …
Cytokines play a key role in its pathogenesis. They contribute to the induction and …
Targeting GM-CSF in inflammatory diseases
IP Wicks, AW Roberts - Nature Reviews Rheumatology, 2016 - nature.com
Granulocyte-macrophage colony stimulating factor (GM-CSF) is a growth factor first
identified as an inducer of differentiation and proliferation of granulocytes and macrophages …
identified as an inducer of differentiation and proliferation of granulocytes and macrophages …
CD123 as a therapeutic target in the treatment of hematological malignancies
U Testa, E Pelosi, G Castelli - Cancers, 2019 - mdpi.com
The interleukin-3 receptor alpha chain (IL-3Rα), more commonly referred to as CD123, is
widely overexpressed in various hematological malignancies, including acute myeloid …
widely overexpressed in various hematological malignancies, including acute myeloid …
Dual role of GM-CSF as a pro-inflammatory and a regulatory cytokine: implications for immune therapy
P Bhattacharya, I Budnick, M Singh… - Journal of Interferon & …, 2015 - liebertpub.com
Granulocyte macrophage colony stimulating factor (GM-CSF) is generally recognized as an
inflammatory cytokine. Its inflammatory activity is primarily due its role as a growth and …
inflammatory cytokine. Its inflammatory activity is primarily due its role as a growth and …
Insights into cytokine–receptor interactions from cytokine engineering
Cytokines exert a vast array of immunoregulatory actions critical to human biology and
disease. However, the desired immunotherapeutic effects of native cytokines are often …
disease. However, the desired immunotherapeutic effects of native cytokines are often …
Recent progress in GM-CSF-based cancer immunotherapy
Cancer immunotherapy is a growing field. GM-CSF, a potent cytokine promoting the
differentiation of myeloid cells, can also be used as an immunostimulatory adjuvant to elicit …
differentiation of myeloid cells, can also be used as an immunostimulatory adjuvant to elicit …
Цитокины в патогенезе и лечении заболеваний человека
АС Симбирцев - 2018 - elibrary.ru
В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …
процессов, защитных реакций организма и в патогенезе иммунопатологических …
The effect of cytokines on osteoblasts and osteoclasts in bone remodeling in osteoporosis: A review
J Xu, L Yu, F Liu, L Wan, Z Deng - Frontiers in Immunology, 2023 - frontiersin.org
The complicated connections and cross talk between the skeletal system and the immune
system are attracting more attention, which is developing into the field of Osteoimmunology …
system are attracting more attention, which is developing into the field of Osteoimmunology …
Pivotal roles of GM‐CSF in autoimmunity and inflammation
A Shiomi, T Usui - Mediators of inflammation, 2015 - Wiley Online Library
Granulocyte macrophage‐colony stimulating factor (GM‐CSF) is a hematopoietic growth
factor, which stimulates the proliferation of granulocytes and macrophages from bone …
factor, which stimulates the proliferation of granulocytes and macrophages from bone …