Phage display screening of therapeutic peptide for cancer targeting and therapy

PE Saw, EW Song - Protein & cell, 2019 - academic.oup.com
Recently, phage display technology has been announced as the recipient of Nobel Prize in
Chemistry 2018. Phage display technique allows high affinity target-binding peptides to be …

Advances in receptor‐mediated, tumor‐targeted drug delivery

DE Large, JR Soucy, J Hebert… - Advanced …, 2019 - Wiley Online Library
Receptor‐mediated drug delivery presents an opportunity to enhance therapeutic efficiency
by accumulating drug within the tissue of interest and reducing undesired, off‐target effects …

Enzyme-responsive polymeric micelles of cabazitaxel for prostate cancer targeted therapy

A Barve, A Jain, H Liu, Z Zhao, K Cheng - Acta biomaterialia, 2020 - Elsevier
Cabazitaxel, a novel tubulin inhibitor with poor affinity for P-glycoprotein, is a second-
generation taxane holding great promise for the treatment of metastatic castration-resistant …

Treating prostate cancer by antibody–drug conjugates

M Rosellini, M Santoni, V Mollica, A Rizzo… - International journal of …, 2021 - mdpi.com
Prostate cancer is the most frequent malignancy in the worldwide male population; it is also
one of the most common among all the leading cancer-related death causes. In the last two …

Preclinical and clinical status of PSMA-targeted alpha therapy for metastatic castration-resistant prostate cancer

A Juzeniene, VY Stenberg, ØS Bruland, RH Larsen - Cancers, 2021 - mdpi.com
Simple Summary Currently, there is no treatment that can cure patients with late stage
metastatic prostate cancer. Prostate-specific membrane antigen is a type of protein …

Targeted radionuclide therapy of prostate cancer—from basic research to clinical perspectives

M Czerwińska, A Bilewicz, M Kruszewski… - Molecules, 2020 - mdpi.com
Prostate cancer is the most commonly diagnosed malignancy in men and the second
leading cause of cancer-related deaths in Western civilization. Although localized prostate …

Leveraging physiology for precision drug delivery

W Sun, Q Hu, W Ji, G Wright, Z Gu - Physiological reviews, 2017 - journals.physiology.org
Physiological characteristics of diseases bring about both challenges and opportunities for
targeted drug delivery. Various drug delivery platforms have been devised ranging from …

Progress in delivery of siRNA-based therapeutics employing nano-vehicles for treatment of prostate cancer

M Ashrafizadeh, K Hushmandi, E Rahmani Moghadam… - Bioengineering, 2020 - mdpi.com
Prostate cancer (PCa) accounts for a high number of deaths in males with no available
curative treatments. Patients with PCa are commonly diagnosed in advanced stages due to …

Targeted delivery to tumors: multidirectional strategies to improve treatment efficiency

OM Kutova, EL Guryev, EA Sokolova, R Alzeibak… - Cancers, 2019 - mdpi.com
Malignant tumors are characterized by structural and molecular peculiarities providing a
possibility to directionally deliver antitumor drugs with minimal impact on healthy tissues and …

Targeted therapeutic nanoparticles: an immense promise to fight against cancer

ST Jahan, SMA Sadat, M Walliser… - Journal of drug …, 2017 - Wiley Online Library
In nanomedicine, targeted therapeutic nanoparticle (NP) is a virtual outcome of
nanotechnology taking the advantage of cancer propagation pattern. Tying up all elements …