• An overview of the current understanding of bleeding and thrombosis in cirrhosis.• An
evidence-based justification for bleeding risk assessment in patients with cirrhosis before …

We conducted systematic reviews of predefined clinical questions and used the Grading of
Recommendations, Assessment, Development and Evaluations approach to develop …

The prevention and management of bleeding and thrombosis in patients with cirrhosis
poses several difficult clinical questions. These Clinical Practice Guidelines have been …

Background The American College of Chest Physicians Clinical Practice Guideline on the
Perioperative Management of Antithrombotic Therapy addresses 43 Patients-Interventions …

Prolonged prothrombin time and thrombocytopenia are common in patients with cirrhosis.
These parameters do not reflect the overall hemostatic rebalance or bleeding risk in the …

Hospitalised patients with decompensated cirrhosis are in a rebalanced haemostatic state
due to a parallel decline in both pro-and anti-haemostatic pathways. However, this …

Patients with cirrhosis develop complex alterations in primary hemostasis that include both
hypocoagulable and hypercoagulable features. This includes thrombocytopenia, multiple …

Abstract The Perioperative Anticoagulation Use for Surgery Evaluation (PAUSE) study
prospectively evaluated a prespecified periprocedural-interruption strategy of direct oral …

Abstract Aim The “2024 aha/acc/acs/asnc/hrs/sca/scct/scmr/svm Guideline for Perioperative
Cardiovascular Management for Noncardiac Surgery” provides recommendations to guide …

Insertion of venous access devices (VAD) is usually considered a procedure with low risk of
bleeding. Nonetheless, insertion of some devices is invasive enough to be associated with …