Anthracyclines, especially doxorubicin and daunorubicin, are the drugs of first choice in the
treatment of patients with hematologic malignancies, soft-tissue sarcomas, and solid tumors …

2D (Two-dimensional), 3D (Three-dimensional), ASE (American Society of
Echocardiography), CAC (Coronary artery calcium), CCT (Cardiovascular computed …

The aim of this study was to investigate the usefulness of three-dimensional (3D) speckle
tracking echocardiography (STE) for assessment of both left and right ventricular systolic …

Aims Little is known about right ventricular (RV) function in survivors of childhood cancer,
although both anthracyclines and radiotherapy represent potentially cardiotoxic treatment …

Background: Daunorubicine, a type of anthracycline, is a drug commonly used in cancer
chemotherapy that increases survival rate but consequently compromises with …

Improvement in long-term survival in patients with acute childhood leukemia has led to the
need for monitorization of chemotherapy-related morbidity and mortality. This study included …

Cancer treatment with Doxorubicin (DOX) is limited due its dose-dependent cardiotoxicity,
mainly related to the oxidative stress production. In experimental models of DOX treatment …

Objectives Cardiotoxicity is a frequent complication secondary to the use of anthracyclines
for cancer chemotherapy. Evidence suggests that certain polymorphic genetic variants …

Background: Acute leukemias are the most frequent malignancies in children. Advances in
treatment have improved the overall survival to 80%. Almost 10% of children with cancer …

Longitudinal motion significantly contributes to the contraction of the ventricles. We studied
the left (LV) and right ventricular (RV) longitudinal functions in 75 anthracycline-exposed …