IMI–myopia genetics report

MS Tedja, AEG Haarman… - … & visual science, 2019 - iovs.arvojournals.org
IMI – Myopia Genetics Report | IOVS | ARVO Journals iovs Issues Topics For Authors About
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[HTML][HTML] An overview of myopia genetics

XB Cai, SR Shen, DF Chen, Q Zhang, ZB Jin - Experimental eye research, 2019 - Elsevier
Myopia is one of the leading ocular disorders causing visual impairment worldwide, with the
prevalence increasing rapidly. It's a significant global public health concern in 21st century …

[HTML][HTML] Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

MS Tedja, R Wojciechowski, PG Hysi, N Eriksson… - Nature …, 2018 - nature.com
Refractive errors, including myopia, are the most frequent eye disorders worldwide and an
increasingly common cause of blindness. This genome-wide association meta-analysis in …

[HTML][HTML] Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

VJM Verhoeven, PG Hysi, R Wojciechowski, Q Fan… - Nature …, 2013 - nature.com
Refractive error is the most common eye disorder worldwide and is a prominent cause of
blindness. Myopia affects over 30% of Western populations and up to 80% of Asians. The …

Prevention and management of myopia and myopic pathology

SM Saw, S Matsumura… - … ophthalmology & visual …, 2019 - iovs.arvojournals.org
Myopia is fast becoming a global public health burden with its increasing prevalence,
particularly in developed countries. Globally, the prevalence of myopia and high myopia …

Genome-wide analysis points to roles for extracellular matrix remodeling, the visual cycle, and neuronal development in myopia

AK Kiefer, JY Tung, CB Do, DA Hinds… - PLoS …, 2013 - journals.plos.org
Myopia, or nearsightedness, is the most common eye disorder, resulting primarily from
excess elongation of the eye. The etiology of myopia, although known to be complex, is …

Myopia genetics and heredity

YM Wang, SY Lu, XJ Zhang, LJ Chen, CP Pang… - Children, 2022 - mdpi.com
Myopia is the most common eye condition leading to visual impairment and is greatly
influenced by genetics. Over the last two decades, more than 400 associated gene loci have …

Deep whole-genome sequencing of 100 southeast Asian Malays

LP Wong, RTH Ong, WT Poh, X Liu, P Chen… - The American Journal of …, 2013 - cell.com
Whole-genome sequencing across multiple samples in a population provides an
unprecedented opportunity for comprehensively characterizing the polymorphic variants in …

[HTML][HTML] Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

CY Cheng, M Schache, MK Ikram, TL Young… - The American Journal of …, 2013 - cell.com
Refractive errors are common eye disorders of public health importance worldwide. Ocular
axial length (AL) is the major determinant of refraction and thus of myopia and hyperopia …

[HTML][HTML] Insight into the molecular genetics of myopia

J Li, Q Zhang - Molecular vision, 2017 - ncbi.nlm.nih.gov
Myopia is the most common cause of visual impairment worldwide. Genetic and
environmental factors contribute to the development of myopia. Studies on the molecular …