Non-isoflavone phytochemicals in soy and their health effects

J Kang, TM Badger, MJJ Ronis… - Journal of agricultural and …, 2010 - ACS Publications
Epidemiological and clinical studies have linked consumption of soy foods with low
incidences of a number of chronic diseases, such as cardiovascular diseases, cancer, and …

Biological functionality of soyasaponins and soyasapogenols

C Guang, J Chen, S Sang, S Cheng - Journal of Agricultural and …, 2014 - ACS Publications
Soyasaponins are a group of structurally complex oleanane triterpenoids primarily found in
soybeans and have diverse biological properties. The recent investigations and findings …

Induction of macroautophagy in human colon cancer cells by soybean B-group triterpenoid saponins

AA Ellington, M Berhow, KW Singletary - Carcinogenesis, 2005 - academic.oup.com
The impact of triterpenoid saponins isolated from soybeans on suppression of colon cancer
cell proliferation was evaluated. Experiments were conducted to determine the effects of a …

Saponins in tumor therapy

C Bachran, S Bachran, M Sutherland… - Mini reviews in …, 2008 - ingentaconnect.com
Saponins are plant glycosides with favorable anti-tumorigenic properties. Several saponins
inhibit tumor cell growth by cell cycle arrest and apoptosis with IC50 values of up to 0.2 μM …

Complete quantification of group A and group B soyasaponins in soybeans

MA Berhow, SB Kong, KE Vermillion… - Journal of agricultural …, 2006 - ACS Publications
A combination of high-pressure extraction and preparative chromatography was used to
purify the group A and group B soyasaponins from soy germ for use as analytical standards …

Momordica charantia leaf extract suppresses rat prostate cancer progression in vitro and in vivo

P Pitchakarn, K Ogawa, S Suzuki, S Takahashi… - Cancer …, 2010 - Wiley Online Library
Cancer metastasis is a major cause of death in cancer patients, with invasion as a first step
greatly contributing to the failure of clinical treatments. Any compounds with an inhibitory …

Saponins as tool for improved targeted tumor therapies

H Fuchs, D Bachran, H Panjideh… - Current drug …, 2009 - ingentaconnect.com
Saponins are plant glycosides that consist of a steroid, steroid alkaloid or triterpenoid
aglycone and one or more sugar chains that are covalently linked by glycosidic binding to …

[HTML][HTML] Chemical and biological characterization of oleanane triterpenoids from soy

W Zhang, DG Popovich - Molecules, 2009 - mdpi.com
Soyasaponins are a group of complex and structural diverse oleanane triterpenoids found in
soy (Glycine max) and other legumes. They are primarily classified into two main groups …

Comprehensive review on signaling pathways of dietary saponins in cancer cells suppression

Y Zhou, AA Farooqi, B Xu - Critical Reviews in Food Science and …, 2023 - Taylor & Francis
Nutrigenomics utilizes high-throughput genomic technologies to reveal changes in gene
and protein levels. Excitingly, ever-growing body of scientific findings has provided sufficient …

Bitter Melon (Momordica charantia) Extract Inhibits Tumorigenicity and Overcomes Cisplatin-Resistance in Ovarian Cancer Cells Through Targeting AMPK Signaling …

MMH Yung, FA Ross, DG Hardie… - Integrative cancer …, 2016 - journals.sagepub.com
Objective. Acquired chemoresistance is a major obstacle in the clinical management of
ovarian cancer. Therefore, searching for alternative therapeutic modalities is urgently …