Osteoporosis is defined as a systemic skeletal disease characterized by decreased bone
mass and micro-architectural deterioration leading to increased fracture risk. Osteoporosis …

Type 2 diabetes is associated with increased fracture risk and the mechanisms underlying
the detrimental effects of diabetes on skeletal health are only partially understood …

Increased fracture risk, traditionally associated with type 1 diabetes, has lately been of great
concern in patients with type 2 diabetes. A variable increase in fracture risk has been …

Metformin, an effective hypoglycemic, can modulate different points of malignant mass,
polycystic ovary syndrome (PCOS), cardiovascular diseases, tuberculosis, and nerve …

Persons with type 1 or type 2 diabetes have a significantly higher fracture risk than age‐
matched persons without diabetes, attributed to disease‐specific deficits in the …

Fracture risk is higher in older adults with type 2 diabetes and may be influenced by
treatments for diabetes. Oral anti-diabetic drugs have different effects on bone metabolism …

Due to its pleiotropic effects, the commonly used drug metformin has gained renewed
interest among medical researchers. While metformin is mainly used for the treatment of …

Metformin is a first-line medication for type II diabetes. Numerous studies have shown that
metformin not only has hypoglycemic effects, but also modulates many physiological and …

Type 2 diabetes mellitus (T2DM) is associated with an increased risk of osteoporotic
fractures, resulting in disabilities and increased mortality. The pathophysiological …

Diabetes mellitus is associated with abnormal bone health and an increased risk of fracture
even though patients have normal or higher BMD. The mechanisms behind diabetes …