The antimalarial activity of 1, 2, 4‐trioxolane/trioxane hybrids and dimers: a review

J Fang, F Song, F Wang - Archiv der Pharmazie, 2022 - Wiley Online Library
Malaria, a mosquito‐borne parasitic infection caused by protozoan parasites belonging to
the genus Plasmodium, is a dangerous disease that contributes to millions of hospital visits …

Combating multi-drug resistant malaria parasite by inhibiting falcipain-2 and heme-polymerization: artemisinin-peptidyl vinyl phosphonate hybrid molecules as new …

EK Aratikatla, M Kalamuddin, KC Rana, G Datta… - European Journal of …, 2021 - Elsevier
Artemisinin-based combination therapies (ACTs) have been able to reduce the clinical and
pathological malaria cases in endemic areas around the globe. However, recent reports …

Late‐Stage C(sp2)−H Arylation of Artemisinic Acid and Arteannuin B: Effect of Olefin Migration Towards Synthesis of C‐13 Arylated Artemisinin Derivatives

S Paul, BM Ghodake… - Chemistry–An Asian …, 2023 - Wiley Online Library
In recent years, C− H bond functionalization has emerged as a pivotal tool for late‐stage
functionalization of complex natural products for the synthesis of potent biologically active …

Vers des inhibiteurs fluorés de la cathepsine S pour l'imagerie non invasive de la plaque instable

J Beuscart - 2023 - theses.hal.science
L'athérosclérose est responsable d'une grande partie des événements cardiovasculaires et
provoque chaque année plus de 19 millions de décès. La détection des plaques …

[PDF][PDF] Synthesis and Study Biological Activities of Sulfur-Containing Drugs

ZF Saeed, MY Saleh, GT Sadeek - Rafidain Journal of Science, 2023 - iasj.net
The importance of developing sulfur therapy is crucial to achieving the progress of
pharmaceutical works-functional groups produced from sulfur can be found in a wide range …

Asymmetric Synthesis of γ-Amino-Functionalised Vinyl Sulfones: De Novo Preparation of Cysteine Protease Inhibitors

W Shen, L Cunningham, P Evans - Synthesis, 2022 - thieme-connect.com
The enantioselective azo-based α-amination of an aldehyde followed by a Horner–
Wadsworth–Emmons-based vinyl sulfone formation is reported. The thus obtained optically …

Quinquevalent phosphorus acids

P Bałczewski, K Owsianik - 2024 - books.rsc.org
This chapter covers scientific contributions in quinquevalent organo-phosphorus chemistry
published in the literature in 2021. The review is not comprehensive but shows the most …