Aryl hydrocarbon receptor (AhR) is a transcription factor that is primarily known as an
intracellular sensor of environmental pollution. After five decades, the list of synthetic and …

The diagnosis and treatment of cancer presents a physical and mental burden to the patient,
often involving diagnostic biopsies and surgeries or chemotherapeutic approaches with …

Trophoblast cell surface antigen 2 (Trop2), a transmembrane glycoprotein, plays a dual role
in physiological and pathological processes. In healthy tissues, Trop2 facilitates …

Distinguishing indolent from clinically significant localized prostate cancer is a major clinical
challenge and influences clinical decision-making between treatment and active …

The Trop-2–targeting antibody-drug conjugate (ADC) sacituzumab govitecan (SG) has been
approved by the US Food and Drug Administration and European Medicines Agency for …

Therapeutic approaches targeting proteins on the surface of cancer cells have emerged as
an important strategy for precision oncology. To capitalize on the potential impact of drugs …

Background Epithelial cell adhesion molecule (EpCAM), a well-established marker for
circulating tumor cells, plays a crucial role in the complex process of cancer metastasis. The …

The global incidence of prostate cancer (PCa) is rising. Localized PCa can be managed
through surgical intervention or radiotherapy, but certain patients may experience …

Immunotherapy with checkpoint inhibitors alone or in combination with a variety of agents
such as chemotherapy, poly-ADP ribose polymerase (PARP) inhibitors or novel biologics …

Therapeutic approaches targeting proteins on the surface of cancer cells have emerged as
an important strategy for precision oncology. To fully capitalize on the potential impact of …