The Hippo signaling pathway controls organ size and tumorigenesis through a kinase
cascade that inactivates Yes‐associated protein (YAP). Here, we show that YAP plays a …

As ovarian tumors progress, they undergo a process of dedifferentiation, allowing adaptive
changes in growth and morphology that promote metastasis and chemoresistance. Herein …

Early placenta development involves cytotrophoblast differentiation into extravillous
trophoblast (EVT) and syncytiotrophoblast (STB). Defective trophoblast development and …

Abdominal aortic aneurysm (AAA) is a chronic vascular disease caused by localized
weakening and broadening of the abdominal aorta. AAA is a clearly underdiagnosed …

Although the role of the Hippo signaling pathway in development and tumorigenesis has
been extensively studied in multiple organs, its role in ovarian follicle development remains …

Female subfertility is an increasing reproductive issue worldwide, which is partially related to
abnormal ovarian follicular development. Granulosa cells (GCs), by providing the necessary …

Background Granulosa cell tumors (GCT) are rare malignant ovarian tumors. The two
subtypes, adult and juvenile granulosa cell tumors, differ in clinical and molecular …

The Hippo signaling pathway has been implicated as a conserved regulator of organ size in
both Drosophila and mammals. Yes-associated protein (YAP), the central component of the …

Abstract Yes-associated protein 1 (YAP1) is a major component of the Hippo signaling
pathway. Although the exact extracellular signals that control the Hippo pathway are …

Accumulating evidence indicates that ovarian high-grade serous carcinoma (HGSC)
originates from fallopian tube secretory epithelial cells (FTSECs). However, the molecular …