The nucleoplasm is not homogenous; it consists of many types of nuclear bodies, also
known as nuclear domains or nuclear subcompartments. These self-organizing structures …

Phosphoinositides (PIs) make up only a small fraction of cellular phospholipids, yet they
control almost all aspects of a cell's life and death. These lipids gained tremendous research …

High temperature has become a global concern, which seriously affects the growth and
production of plants, particularly crops. Thus, the molecular mechanism of the heat stress …

The tumour suppressor p53 and PI3K–AKT pathways have fundamental roles in the
regulation of cell growth and apoptosis, and are frequently mutated in cancer. Here, we …

RNA tailing, or the addition of non-templated nucleotides to the 3′ end of RNA, is the most
frequent and conserved type of RNA modification. The addition of tails and their composition …

All cellular compartments are separated from the external environment by a membrane,
which consists of a lipid bilayer. Subcellular structures, including clathrin-coated pits …

ABSTRACT Messenger RNA (mRNA) 3′ end formation is a nuclear process through which
all eukaryotic primary transcripts are endonucleolytically cleaved and most of them acquire a …

Modification of microRNA sequences by the 3′ addition of nucleotides to generate so-
called “isomiRs” adds to the complexity of miRNA function, with recent reports showing that …

Poly (A) tails have long been known as stable 3′ modifications of eukaryotic mRNAs,
added during nuclear pre‐mRNA processing. It is now appreciated that this modification is …

Animal microRNA sequences are subject to 3′ nucleotide addition. Through detailed
analysis of deep-sequenced short RNA data sets, we show adenylation and uridylation of …