Intracellular Sources of ROS/H2O2 in Health and Neurodegeneration: Spotlight on Endoplasmic Reticulum
Reactive oxygen species (ROS) are produced continuously throughout the cell as products
of various redox reactions. Yet these products function as important signal messengers …
of various redox reactions. Yet these products function as important signal messengers …
Hypoxia and mitochondrial dysfunction in pregnancy complications
Hypoxia is a common and severe stress to an organism's homeostatic mechanisms, and
hypoxia during gestation is associated with significantly increased incidence of maternal …
hypoxia during gestation is associated with significantly increased incidence of maternal …
Nitric oxide signaling in pregnancy and preeclampsia
EF Sutton, M Gemmel, RW Powers - Nitric Oxide, 2020 - Elsevier
While the etiology of preeclampsia continues to be elucidated, it is clear that preeclampsia is
a complex obstetrical syndrome associated with maternal vascular dysfunction within which …
a complex obstetrical syndrome associated with maternal vascular dysfunction within which …
[HTML][HTML] First trimester serum biomarker discovery study for early onset, preterm onset and preeclampsia at term
RHJ Beernink, EF Zwertbroek, JHN Schuitemaker… - Placenta, 2022 - Elsevier
Introduction Preeclampsia (PE) is a heterogeneous syndrome during pregnancy and
postpartum and it is subdivided in this study into early onset (< 34 weeks), preterm onset (34 …
postpartum and it is subdivided in this study into early onset (< 34 weeks), preterm onset (34 …
Protein network analysis of whole exome sequencing of severe preeclampsia
J Schuster, GA Tollefson, V Zarate, A Agudelo… - Frontiers in …, 2022 - frontiersin.org
Preeclampsia is a hypertensive disorder of pregnancy, which complicates up to 15% of US
deliveries. It is an idiopathic disorder associated with several different phenotypes. We …
deliveries. It is an idiopathic disorder associated with several different phenotypes. We …
C1q/tumor necrosis factor related protein 6 (CTRP6) regulates the phenotypes of high glucose-induced gestational trophoblast cells via peroxisome proliferator …
J Zhang, WP Bai - Bioengineered, 2022 - Taylor & Francis
Multiple studies have confirmed that adipokines are compactly relevant to insulin resistance
and participate in the pathogenesis of gestational diabetes mellitus (GDM). This paper …
and participate in the pathogenesis of gestational diabetes mellitus (GDM). This paper …
[HTML][HTML] Systematic Proteome Profiling of Maternal Plasma for Development of Preeclampsia Biomarkers
JH Lim, JM Lim, HM Lee, HJ Lee, DW Kwak… - Molecular & Cellular …, 2024 - Elsevier
Preeclampsia (PE) is a hypertensive disorder of pregnancy with various clinical symptoms.
However, traditional markers for the disease including high blood pressure and proteinuria …
However, traditional markers for the disease including high blood pressure and proteinuria …
N-Acetyl-L-cysteine and aminooxyacetic acid differentially modulate toxicity of the trichloroethylene metabolite S-(1, 2-dichlorovinyl)-L-cysteine in human placental …
AL Su, LH Lash, R Loch-Caruso - Toxicology, 2023 - Elsevier
Trichloroethylene (TCE) is a known human carcinogen with toxicity attributed to its
metabolism. S-(1, 2-Dichlorovinyl)-L-cysteine (DCVC) is a metabolite of TCE formed …
metabolism. S-(1, 2-Dichlorovinyl)-L-cysteine (DCVC) is a metabolite of TCE formed …
Large-Scale Proteomics in Early Pregnancy and Hypertensive Disorders of Pregnancy
P Greenland, MR Segal, RB McNeil, CB Parker… - JAMA …, 2024 - jamanetwork.com
Importance There is no consensus regarding the best method for prediction of hypertensive
disorders of pregnancy (HDP), including gestational hypertension and preeclampsia …
disorders of pregnancy (HDP), including gestational hypertension and preeclampsia …
Spatiotemporal Protein Expression Profiles of QSOX1 in the Murine Uterus, Placenta, and Embryo during Pregnancy
HS Lin, RKK Lee, TH Yang, HW Fang, SH Li - Applied Sciences, 2021 - mdpi.com
Quiescin Q6 sulfhydryl oxidase 1 (QSOX1) catalyzes the oxidation of the sulfhydryl group to
disulfide bond and is widely expressed in various tissues. This study focuses on …
disulfide bond and is widely expressed in various tissues. This study focuses on …