Myostatin as a biomarker of muscle wasting and other pathologies-state of the art and knowledge gaps
J Baczek, M Silkiewicz, ZB Wojszel - Nutrients, 2020 - mdpi.com
Sarcopenia is a geriatric syndrome with a significant impact on older patients' quality of life,
morbidity and mortality. Despite the new available criteria, its early diagnosis remains …
morbidity and mortality. Despite the new available criteria, its early diagnosis remains …
Activin A: an emerging target for improving cancer treatment?
A Ries, K Schelch, D Falch, L Pany… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction Activin A is involved in the regulation of a surprisingly broad number of
processes that are relevant for cancer development and treatment; it is implicated in cell …
processes that are relevant for cancer development and treatment; it is implicated in cell …
The prognostic value of pre-treatment circulating biomarkers of systemic inflammation (CRP, dNLR, YKL-40, and IL-6) in vulnerable older patients with metastatic …
G Liposits, H Skuladottir, J Ryg, SB Winther… - Journal of clinical …, 2022 - mdpi.com
Appropriate patient selection for palliative chemotherapy is crucial in patients with metastatic
colorectal cancer (mCRC). We investigated the prognostic value of C-reactive protein (CRP) …
colorectal cancer (mCRC). We investigated the prognostic value of C-reactive protein (CRP) …
Serum Interleukins 8, 17, and 33 as Potential Biomarkers of Colon Cancer
Simple Summary This research studied how three types of proteins, called interleukins
(namely 8, 17A and 33), are present in the blood of healthy people and people with colon …
(namely 8, 17A and 33), are present in the blood of healthy people and people with colon …
[HTML][HTML] The association of blood biomarkers with treatment response and adverse health outcomes in older patients with solid tumors: A systematic review
Y van Holstein, PJE van den Berkmortel… - Journal of Geriatric …, 2023 - Elsevier
Introduction Blood biomarkers are potentially useful prognostic markers and may support
treatment decisions, but it is unknown if and which biomarkers are most useful in older …
treatment decisions, but it is unknown if and which biomarkers are most useful in older …
Depletion of skeletal muscle mass adversely affects long-term outcomes for men undergoing gastrectomy for gastric cancer
K Sakurai, N Kubo, Y Tamamori, N Aomatsu, T Nishii… - PLoS …, 2021 - journals.plos.org
Background Although low skeletal muscle mass has an adverse impact on the treatment
outcomes of cancer patients, whether the relationship between preoperative skeletal muscle …
outcomes of cancer patients, whether the relationship between preoperative skeletal muscle …
Role of FGF receptors and their pathways in adrenocortical tumors and possible therapeutic implications
I Sbiera, S Kircher, B Altieri, K Lenz, C Hantel… - Frontiers in …, 2021 - frontiersin.org
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy and treatment of advanced
disease is challenging. Clinical trials with multi-tyrosine kinase inhibitors in the past have …
disease is challenging. Clinical trials with multi-tyrosine kinase inhibitors in the past have …
Low myostatin serum levels are associated with poor outcome in critically ill patients
TH Wirtz, SH Loosen, L Buendgens, B Kurt… - Diagnostics, 2020 - mdpi.com
Background: Growth differentiation factor 8, GDF-8 (Myostatin), is a protein released by
myocytes inhibiting muscle growth and differentiation. Serum concentrations of Myostatin …
myocytes inhibiting muscle growth and differentiation. Serum concentrations of Myostatin …
The effect of vitamin D supplementation on serum levels of fibroblast growth factor-23: A systematic review and meta-analysis of randomized controlled trials
F Meshkini, S Soltani, CCT Clark, V Tam… - The Journal of steroid …, 2022 - Elsevier
Previous studies of the effect of vtamin D on serum levels of fibroblast growth factor-23 (FGF-
23) have yeilded an inconsistent findings. This systematic review and meta-analysis of …
23) have yeilded an inconsistent findings. This systematic review and meta-analysis of …
[HTML][HTML] Association of circulating fibroblast growth factor 21 levels with all-cause and cardiovascular mortality: The multi-ethnic study of atherosclerosis
WJ Tucker, B Tucker, AS Januszewski, AJ Jenkins… - Clinica Chimica …, 2024 - Elsevier
Background Fibroblast growth factor 21 (FGF21) levels are often elevated in cardiovascular
disease (CVD). However, no study has assessed its association with cardiovascular and all …
disease (CVD). However, no study has assessed its association with cardiovascular and all …