Myostatin as a biomarker of muscle wasting and other pathologies-state of the art and knowledge gaps

J Baczek, M Silkiewicz, ZB Wojszel - Nutrients, 2020 - mdpi.com
Sarcopenia is a geriatric syndrome with a significant impact on older patients' quality of life,
morbidity and mortality. Despite the new available criteria, its early diagnosis remains …

Activin A: an emerging target for improving cancer treatment?

A Ries, K Schelch, D Falch, L Pany… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction Activin A is involved in the regulation of a surprisingly broad number of
processes that are relevant for cancer development and treatment; it is implicated in cell …

The prognostic value of pre-treatment circulating biomarkers of systemic inflammation (CRP, dNLR, YKL-40, and IL-6) in vulnerable older patients with metastatic …

G Liposits, H Skuladottir, J Ryg, SB Winther… - Journal of clinical …, 2022 - mdpi.com
Appropriate patient selection for palliative chemotherapy is crucial in patients with metastatic
colorectal cancer (mCRC). We investigated the prognostic value of C-reactive protein (CRP) …

Serum Interleukins 8, 17, and 33 as Potential Biomarkers of Colon Cancer

CD Tâlvan, L Budișan, ET Tâlvan, V Grecu, O Zănoagă… - Cancers, 2024 - mdpi.com
Simple Summary This research studied how three types of proteins, called interleukins
(namely 8, 17A and 33), are present in the blood of healthy people and people with colon …

[HTML][HTML] The association of blood biomarkers with treatment response and adverse health outcomes in older patients with solid tumors: A systematic review

Y van Holstein, PJE van den Berkmortel… - Journal of Geriatric …, 2023 - Elsevier
Introduction Blood biomarkers are potentially useful prognostic markers and may support
treatment decisions, but it is unknown if and which biomarkers are most useful in older …

Depletion of skeletal muscle mass adversely affects long-term outcomes for men undergoing gastrectomy for gastric cancer

K Sakurai, N Kubo, Y Tamamori, N Aomatsu, T Nishii… - PLoS …, 2021 - journals.plos.org
Background Although low skeletal muscle mass has an adverse impact on the treatment
outcomes of cancer patients, whether the relationship between preoperative skeletal muscle …

Role of FGF receptors and their pathways in adrenocortical tumors and possible therapeutic implications

I Sbiera, S Kircher, B Altieri, K Lenz, C Hantel… - Frontiers in …, 2021 - frontiersin.org
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy and treatment of advanced
disease is challenging. Clinical trials with multi-tyrosine kinase inhibitors in the past have …

Low myostatin serum levels are associated with poor outcome in critically ill patients

TH Wirtz, SH Loosen, L Buendgens, B Kurt… - Diagnostics, 2020 - mdpi.com
Background: Growth differentiation factor 8, GDF-8 (Myostatin), is a protein released by
myocytes inhibiting muscle growth and differentiation. Serum concentrations of Myostatin …

The effect of vitamin D supplementation on serum levels of fibroblast growth factor-23: A systematic review and meta-analysis of randomized controlled trials

F Meshkini, S Soltani, CCT Clark, V Tam… - The Journal of steroid …, 2022 - Elsevier
Previous studies of the effect of vtamin D on serum levels of fibroblast growth factor-23 (FGF-
23) have yeilded an inconsistent findings. This systematic review and meta-analysis of …

[HTML][HTML] Association of circulating fibroblast growth factor 21 levels with all-cause and cardiovascular mortality: The multi-ethnic study of atherosclerosis

WJ Tucker, B Tucker, AS Januszewski, AJ Jenkins… - Clinica Chimica …, 2024 - Elsevier
Background Fibroblast growth factor 21 (FGF21) levels are often elevated in cardiovascular
disease (CVD). However, no study has assessed its association with cardiovascular and all …