[HTML][HTML] Impact of heavy metals on the environment and human health: Novel therapeutic insights to counter the toxicity
Heavy metals are well-known environmental pollutants owing to their toxicity, longevity in
the atmosphere, and ability to accumulate in the human body via bioaccumulation. The …
the atmosphere, and ability to accumulate in the human body via bioaccumulation. The …
[HTML][HTML] The therapeutic potential of apigenin
Several plant bioactive compounds have exhibited functional activities that suggest they
could play a remarkable role in preventing a wide range of chronic diseases. The largest …
could play a remarkable role in preventing a wide range of chronic diseases. The largest …
[HTML][HTML] The essential elements of Alzheimer's disease
Treatments for Alzheimer's disease (AD) directed against the prominent amyloid plaque
neuropathology are yet to be proved effective despite many phase 3 clinical trials. There are …
neuropathology are yet to be proved effective despite many phase 3 clinical trials. There are …
[HTML][HTML] Recent advances in the inhibition of p38 MAPK as a potential strategy for the treatment of Alzheimer's disease
P38 mitogen-activated protein kinase (MAPK) is a crucial target for chronic inflammatory
diseases. Alzheimer's disease (AD) is characterized by the presence of amyloid plaques …
diseases. Alzheimer's disease (AD) is characterized by the presence of amyloid plaques …
Health functionality of apigenin: A review
Apigenin is being used by humans in the form of plant extract for the treatment of a number
of disorders and inflammatory conditions, until its discovery as a core compound. Apigenin …
of disorders and inflammatory conditions, until its discovery as a core compound. Apigenin …
Natural products against Alzheimer's disease: Pharmaco-therapeutics and biotechnological interventions
A Dey, R Bhattacharya, A Mukherjee… - Biotechnology advances, 2017 - Elsevier
Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease
associated with memory and cognition impairment ultimately leading to death. It is the …
associated with memory and cognition impairment ultimately leading to death. It is the …
[HTML][HTML] Neuroprotective effect of artichoke-based nanoformulation in sporadic Alzheimer's disease mouse model: focus on antioxidant, anti-inflammatory, and …
The vast socio-economic impact of Alzheimer's disease (AD) has prompted the search for
new neuroprotective agents with good tolerability and safety profile. With its outstanding role …
new neuroprotective agents with good tolerability and safety profile. With its outstanding role …
[HTML][HTML] Neuroprotective, anti-amyloidogenic and neurotrophic effects of apigenin in an Alzheimer's disease mouse model
L Zhao, JL Wang, R Liu, XX Li, JF Li, L Zhang - Molecules, 2013 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by extracellular
senile plaques and intracellular neurofibrillary tangles in the brain. Amyloid-β peptides (Aβ) …
senile plaques and intracellular neurofibrillary tangles in the brain. Amyloid-β peptides (Aβ) …
[HTML][HTML] Pharmacological and molecular insight on the cardioprotective role of apigenin
Apigenin is a naturally occurring dietary flavonoid found abundantly in fruits and vegetables.
It possesses a wide range of biological properties that exert antioxidant, anti-inflammatory …
It possesses a wide range of biological properties that exert antioxidant, anti-inflammatory …
[HTML][HTML] Protein folding and aggregation into amyloid: the interference by natural phenolic compounds
M Stefani, S Rigacci - International journal of molecular sciences, 2013 - mdpi.com
Amyloid aggregation is a hallmark of several degenerative diseases affecting the brain or
peripheral tissues, whose intermediates (oligomers, protofibrils) and final mature fibrils …
peripheral tissues, whose intermediates (oligomers, protofibrils) and final mature fibrils …