Cadherins are a family of cell adhesion receptors that are crucial for the mutual association
of vertebrate cells. Through their homophilic binding interactions, cadherins play a role in …

Functional recovery from peripheral nerve injury and repair depends on a multitude of
factors, both intrinsic and extrinsic to neurons. Neuronal survival after axotomy is a …

Astrocytic brain tumours, including glioblastomas, are incurable neoplasms characterized by
diffusely infiltrative growth. Here we show that many tumour cells in astrocytomas extend …

The animal body is a collective of heterogeneous cell types. The heterotypic cells are
arranged in a precise order to form tissue structures in which the cells never intermix …

Neurons have long held the spotlight as the central players of the nervous system, but we
must remember that we have equal numbers of astrocytes and neurons in the brain. Are …

The development of techniques to create and use multiphase microstructured hydrogels
(granular hydrogels or microgels) has enabled the generation of cultures with more …

beta 1 integrins are cell-surface receptors that mediate cell-cell and cell-matrix interactions.
We have generated a null mutation in the gene for the beta 1 integrin subunit in mice and …

Cadherins are Ca2+-dependent cell-cell adhesion molecules that play critical roles in
animal morphogenesis. Various cadherin-related molecules have also been identified …

Peripheral nerve regeneration comprises the formation of axonal sprouts, their outgrowth as
regenerating axons and the reinnervation of original targets. This review focuses on the …

The development of neurons and virtually all other cell types in the organism depends upon
interactions with molecules in their environment. Studics of individual cell types have …