Biocompatibility of ionic liquids towards protein stability: A comprehensive overview on the current understanding and their implications

A Kumar, M Bisht, P Venkatesu - International journal of biological …, 2017 - Elsevier
Over the past years since the discovery of ionic liquids (ILs), there is an increased demand
to consider ILs as novel biocompatible co-solvents for proteins. Due to their tunable physical …

The influence of sodium phosphate buffer on the stability of various proteins: Insights into protein-buffer interactions

P Pavani, K Kumar, A Rani, P Venkatesu… - Journal of Molecular …, 2021 - Elsevier
Present study delineates the effects of sodium phosphate buffer (PBS) solutions on the
stability of various proteins including lysozyme (Lys), bromelain (BM), hemoglobin (Hb), and …

Biocompatibility of surface-modified gold nanoparticles towards red blood cells and haemoglobin

S Kumar, I Jha, NK Mogha, P Venkatesu - Applied Surface Science, 2020 - Elsevier
Studies related to corona formation have been carried out largely for proteins and
nanomaterials, however specific studies about the synthesis of nano-systems with bio …

A spectroscopic and molecular dynamics simulation approach towards the stabilizing effect of ammonium-based ionic liquids on bovine serum albumin

L Satish, S Millan, K Bera, S Mohapatra… - New Journal of …, 2017 - pubs.rsc.org
In this article, we have explored the impact of ammonium-based ionic liquids (ILs) on the
thermal unfolding/refolding of bovine serum albumin (BSA) in aqueous solutions using …

Aromatic vs alicyclic: hydrophobicity of the ionic liquid on protein stability and fibril formation

P Kushwaha, NP Prabhu - Journal of Molecular Liquids, 2024 - Elsevier
Ionic liquids (ILs) are environment-friendly solvents with potential applications in
biochemical reactions and as pharmaceutical ingredients. They are used to stabilize …

Unprecedented improvement in the stability of hemoglobin in the presence of promising green solvent 1-allyl-3-methylimidazolium chloride

I Jha, P Venkatesu - ACS Sustainable Chemistry & Engineering, 2016 - ACS Publications
In this article, we have explored the influence of a peculiar member of imidazolium-based
ionic liquid (IL), 1-allyl-3-methylimidazolium chloride ([Amim][Cl]), on the stability of …

Exploring the structure and stability of amino acids and glycine peptides in biocompatible ionic liquids

A Kumar, M Bisht, P Venkatesu - RSC advances, 2016 - pubs.rsc.org
Amino acids (AAs) are vital components for a variety of biological systems and can be linked
through covalent bonds (or peptide bonds) to form a protein structure. Essentially, the …

Imidazolium-based ionic liquids with increasing alkyl chain length of cations decrease the stability and fibrillation propensity of lysozyme

P Kushwaha, NP Prabhu - New Journal of Chemistry, 2022 - pubs.rsc.org
Ionic liquids (ILs) are neoteric solvents with a wide range of applications. Interaction of ILs
with proteins alters their stability and self-aggregation. The present work analyses the effect …

Molecular characterization of the effects of Ganoderma Lucidum polysaccharides on the structure and activity of bovine serum albumin

Y Wang, Y Wang, Q Luo, H Zhang, J Cao - Spectrochimica Acta Part A …, 2019 - Elsevier
The investigation about polysaccharides-protein system is attributed to numerous very
important applications for pharmaceutical, food, chemical and other industries. In the present …

Surface active ionic liquid induced conformational transition in aqueous medium of hemoglobin

R Vashishat, S Chabba, RK Mahajan - RSC advances, 2017 - pubs.rsc.org
The interaction of human hemoglobin (Hb) with surface active ionic liquids (SAILs), 1-
dodecyl-3-methylimidazolium chloride [C12mim][Cl] and 1-hexyl-3-methylimidazolium …