Primary, secondary, and tertiary interventions to reduce the morbidity and mortality of preterm birth

JD Iams, R Romero, JF Culhane, RL Goldenberg - The lancet, 2008 - thelancet.com
Interventions to reduce the morbidity and mortality of preterm birth can be primary (directed
to all women), secondary (aimed at eliminating or reducing existing risk), or tertiary …

Betamimetics for inhibiting preterm labour

JP Neilson, HM West… - Cochrane Database of …, 2014 - cochranelibrary.com
Background Preterm birth is a major contributor to perinatal mortality and morbidity
worldwide. Tocolytic agents are drugs used to inhibit uterine contractions. Betamimetics are …

[PDF][PDF] WHO recommendations on interventions to improve preterm birth outcomes

World Health Organization - 2015 - apps.who.int
Preterm babies are prone to serious illness or death during the neonatal period. Without
appropriate treatment, those who survive are at increased risk of lifelong disability and poor …

A novel molecular microbiologic technique for the rapid diagnosis of microbial invasion of the amniotic cavity and intra‐amniotic infection in preterm labor with intact …

R Romero, J Miranda… - American journal of …, 2014 - Wiley Online Library
Problem The diagnosis of microbial invasion of the amniotic cavity (MIAC) has been
traditionally performed using traditional cultivation techniques, which require growth of …

Nifedipine in the management of preterm labor: a systematic review and metaanalysis

A Conde-Agudelo, R Romero, JP Kusanovic - American journal of …, 2011 - Elsevier
OBJECTIVE: To determine the efficacy and safety of nifedipine as a tocolytic agent in women
with preterm labor. STUDY DESIGN: A systematic review and metaanalysis of randomized …

Tocolytics for preterm premature rupture of membranes

AD Mackeen, J Seibel‐Seamon… - Cochrane Database …, 2011 - cochranelibrary.com
Background In women with preterm labor, tocolysis has not been shown to improve perinatal
mortality; however, it is often given for 48 hours to allow for the corticosteroid effect for fetal …

Care for women with prior preterm birth

JD Iams, V Berghella - American journal of obstetrics and gynecology, 2010 - Elsevier
Women who have delivered an infant between 16 and 36 weeks' gestation have an
increased risk of preterm birth in subsequent pregnancies. The risk increases with more than …

Magnesium maintenance therapy for preventing preterm birth after threatened preterm labour

S Han, CA Crowther, V Moore - Cochrane Database of …, 2013 - cochranelibrary.com
Background Magnesium maintenance therapy is one of the types of tocolytic therapy used
after an episode of threatened preterm labour (usually treated with an initial dose of tocolytic …

[HTML][HTML] Landscape of preterm birth therapeutics and a path forward

BS Coler, O Shynlova, A Boros-Rausch, S Lye… - Journal of Clinical …, 2021 - mdpi.com
Preterm birth (PTB) remains the leading cause of infant morbidity and mortality. Despite 50
years of research, therapeutic options are limited and many lack clear efficacy. Tocolytic …

[HTML][HTML] The preterm parturition syndrome and its implications for understanding the biology, risk assessment, diagnosis, treatment and prevention of preterm birth

F Gotsch, F Gotsch, R Romero, O Erez… - The Journal of …, 2009 - Taylor & Francis
The syndromic nature of spontaneous labour was a concept first proposed in 1994 [1]. It has
important implications for understanding the biology of preterm parturition, and also, setting …