Reperfusion of ischaemic tissues is often associated with microvascular dysfunction that is
manifested as impaired endothelium‐dependent dilation in arterioles, enhanced fluid …

There are two components to the reperfusion syndrome, which follows extremity ischemia.
The local response, which follows reperfusion, consists of limb swelling with its potential for …

Diabetic retinopathy is a leading cause of adult vision loss and blindness. Much of the retinal
damage that characterizes the disease results from retinal vascular leakage and …

Platelets, besides their specialised role in haemostasis and atherothrombosis, actively
modulate innate and adaptive immune responses with crucial roles in immune surveillance …

The accumulation of leukocytes in inflamed tissue results from adhesive interactions
between leukocytes and endothelial cells within the microcirculation. These adhesive …

Cardiovascular diseases are known to be the most fatal diseases worldwide.
Ischaemia/reperfusion (I/R) injury is at the centre of the pathology of the most common …

A decrease in serum albumin concentrations is an almost inevitable finding in disease
states, and is primarily mediated in the acute phase by alterations in vascular permeability …

purpose. The objectives of this study were to characterize the differential potency of two
major VEGF isoforms, VEGF 120 and VEGF 164, for inducing leukocyte stasis (leukostasis) …

A variety of recently discovered glycoproteins have been implicated in cell-cell interactions
that are critical for normal hemostasis, immune surveillance, and vascular wall integrity …

Leukocyte emigration into lymphatic tissues or inflammatory sites is regulated by the
expression of adhesion and signaling molecules (1). Binding of selectins to cell-surface …