The discrete and random occurrence of chemical reactions far from thermodynamic
equilibrium, and low copy numbers of chemical species, in systems biology necessitate …

The eukaryotic cell cycle is robustly designed, with interacting molecules organized within a
definite topology that ensures temporal precision of its phase transitions. Its underlying …

While ordinary differential equations (ODEs) form the conceptual framework for modelling
many cellular processes, specific situations demand stochastic models to capture the …

Applying the mathematical circulation theory of Markov chains, we investigate the
synchronized stochastic dynamics of a discrete network model of yeast cell-cycle regulation …

Актуальность поиска новых мишеней противоопухолевых препаратов обусловлена
низкой эффективностью существующей терапии. Нами предложен и реализован в …

During the past decade, many successful deterministic models of macromolecular regulatory
networks have been built. Deterministic simulations of these models can show only average …

The eukaryotic cell cycle is robustly designed, with interacting molecules organized within a
definite topology that ensures temporal precision of its phase transitions. Its underlying …

This thesis work contributes the first vital steps in the development of a biologically based
proliferation model to advance a bioartificial tissue regeneration model. Specifically, this …