Overcoming barriers by local drug delivery with liposomes

SG Antimisiaris, A Marazioti, M Kannavou… - Advanced drug delivery …, 2021 - Elsevier
Localized or topical administration of drugs may be considered as a potential approach for
overcoming the problems caused by the various biological barriers encountered in drug …

[HTML][HTML] Polysaccharide hydrogel platforms as suitable carriers of liposomes and extracellular vesicles for dermal applications

LP Jahromi, M Rothammer, G Fuhrmann - Advanced Drug Delivery …, 2023 - Elsevier
Lipid-based nanocarriers have been extensively investigated for their application in drug
delivery. Particularly, liposomes are now clinically established for treating various diseases …

Optimization and evaluation of propolis liposomes as a promising therapeutic approach for COVID-19

H Refaat, FM Mady, HA Sarhan, HS Rateb… - International journal of …, 2021 - Elsevier
The present work aimed to develop an optimized liposomal formulation for enhancing the
anti-viral activity of propolis against COVID-19. Docking studies were performed for certain …

Cubosomes: composition, preparation, and drug delivery applications.

SA Gaballa, OH El Garhy… - Journal of advanced …, 2020 - jabps.journals.ekb.eg
Cubosomes can be considered as a novel lipid-based nanosystems similar to well-known
vesicular systems such as liposomes and niosomes. Cubosomes have been widely …

Topical nano-vesicular spanlastics of celecoxib: Enhanced anti-inflammatory effect and down-regulation of TNF-α, NF-кB and COX-2 in complete Freund's adjuvant …

E Alaaeldin, HA Abou-Taleb, SA Mohamad… - International Journal …, 2021 - Taylor & Francis
Background Rheumatoid arthritis (RA) is an autoimmune disease that underlies chronic
inflammation of the synovial membrane. Non-steroidal anti-inflammatory drugs (NSAIDs) are …

[HTML][HTML] The potential effects of quercetin-loaded nanoliposomes on amoxicillin/clavulanate-induced hepatic damage: targeting the Sirt1/Nrf2/Nf-κB signaling pathway …

MM Abd El-Emam, M Mostafa, AA Farag, HS Youssef… - Antioxidants, 2023 - mdpi.com
Amoxicillin/clavulanate (Co-Amox), a commonly used antibiotic for the treatment of bacterial
infections, has been associated with drug-induced liver damage. Quercetin (QR), a naturally …

[HTML][HTML] Dermal drug delivery of phytochemicals with phenolic structure via lipid-based nanotechnologies

V Gugleva, N Ivanova, Y Sotirova, V Andonova - Pharmaceuticals, 2021 - mdpi.com
Phenolic compounds are a large, heterogeneous group of secondary metabolites found in
various plants and herbal substances. From the perspective of dermatology, the most …

[HTML][HTML] Recent advances of ocular drug delivery systems: prominence of ocular implants for chronic eye diseases

M Mostafa, A Al Fatease, RG Alany, H Abdelkader - Pharmaceutics, 2023 - mdpi.com
Chronic ocular diseases can seriously impact the eyes and could potentially result in
blindness or serious vision loss. According to the most recent data from the WHO, there are …

Development and optimization of besifloxacin hydrochloride loaded liposomal gel prepared by thin film hydration method using 32 full factorial design

A Bhattacharjee, PJ Das, S Dey, AK Nayak… - Colloids and Surfaces A …, 2020 - Elsevier
The objective of this present research work was to develop and optimize a liposomal gel
containing a fourth generation fluoroquinolone antibiotic, besifloxacin hydrochloride (BSF …

Novel thymoquinone loaded chitosan-lecithin micelles for effective wound healing: Development, characterization, and preclinical evaluation

P Negi, G Sharma, C Verma, P Garg, C Rathore… - Carbohydrate …, 2020 - Elsevier
While the wound healing activity of thymoquinone (TQ) is well known, its clinical
effectiveness remains limited due to the inherently low aqueous solubility, resulting in …