Privileged structures have been widely used as an effective template for the research and
discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and …

Cancer is one of the leading health hazards and the prominent cause of death in the world.
A number of anticancer agents are currently in clinical practice and used for treatment of …

Coumarin enjoys an important place in drug discovery process due to its presence in
diversity of biologically active compounds. Many compounds of plant origin are derivatives …

A series of new coumarin-dithiocarbamate hybrids were designed and synthesized as
multitarget agents for the treatment of Alzheimer's disease. Most of them showed potent and …

Introduction: COX-2 is a key enzyme in the process of prostaglandins (PGs) synthesis. The
products of this enzyme could play a major role as the mediators of the inflammatory …

Cancer chemoprevention is a promising strategy taken to block, reverse, or retard
carcinogenesis. α-Mangostin, a natural xanthone isolated from the pericarps of mangosteen …

The discovery of COX enzymes has led to a better understanding of inflammation and its
related biological pathways. Apart from being related to inflammation and pain, it has also …

The current work presents the synthesis and biological evaluation of new series of coumarin
hydrazide-hydrazone derivatives that showed in vitro broad spectrum antitumor activities …

Natural coumarins and their derivatives isolated from various plants or microorganisms have
inherent antioxidant, antibacterial, antifungal, antiviral and anticancer properties among …

Coumarin class of organic compounds consists of 1, 2-benzopyrone ring system as a basic
parent scaffold. These benzopyrones are subdivided into alpha-benzopyrones and …