Liver transplantation is the ultimate method for treating end-stage liver disease. With the
increasing prevalence of obesity, the number of patients with non-alcoholic fatty liver, a …

Curcumin (diferuloylmethane), an orange-yellow component of turmeric or curry powder, is a
polyphenol natural product isolated from the rhizome of the plant Curcuma longa. For …

Atherosclerosis is an inflammatory process of the vascular wall characterized by the
infiltration of lipids and inflammatory cells. Oxidative modifications of infiltrating low-density …

The heme oxygenases, which consist of constitutive and inducible isozymes (HO-1, HO-2),
catalyze the rate-limiting step in the metabolic conversion of heme to the bile pigments (ie …

Reactive oxygen or nitrogen species (ROS/RNS) generated endogenously or in response to
environmental stress have long been implicated in tissue injury in the context of a variety of …

Over the last decade, studies have unraveled many aspects of endogenous production and
physiological functions of carbon monoxide (CO). The majority of endogenous CO is …

Ischemia–reperfusion–induced lung injury is characterized by nonspecific alveolar damage,
lung edema, and hypoxemia occurring within 72 hours after lung transplantation. The most …

Ischemia-reperfusion injury is, at least in part, responsible for the morbidity associated with
liver surgery under total vascular exclusion or after liver transplantation. The …

Is there any reason to write a third book on the topic of oxygen-ozone therapy? The first was
written four years ago for italian physicians, who, for some time, had complained about the …

Heme oxygenase 1 (HO-1) inhibits apoptosis by regulating cellular prooxidant iron. We now
show that there is an additional mechanism by which HO-1 inhibits apoptosis, namely by …