Angiogenesis is a critical step in the progression of almost all human malignancies and
some other life-threatening diseases. Anti-angiogenic therapy is a novel and effective …

Eye is the unique sense organ with complex and sophisticated anatomy and physiology.
Being most instrumental for vision, it is secured by varied protective barriers; ranging from …

Effective drug delivery to the retina still remains a challenge due to ocular elimination
mechanisms and complex barriers that selectively limit the entry of drugs into the eye. To …

Diabetic retinopathy (DR) is one of the leading causes of blindness worldwide. Multiple
treatment options have been used over time to attempt to modify the natural progression of …

Microfabrication technology has enabled the development of novel controlled‐release
devices that possess an integration of structural, mechanical, and perhaps electronic …

The application of nanotechnology to drug delivery is widespread and expected to change
the landscape of the pharmaceutical and biotechnology industries. Polymer-based …

Topical route of administration is very important and the most commonly used method of
drug delivery for treatment of ocular diseases. However, due to unique anatomical and …

Background: This paper describes the synthesis of thiolated chitosan-based hydrogels with
varying degrees of crosslinking that has been utilized to modulate release kinetics of two …

In recent years, various conventional formulations have been used for the treatment and/or
management of ocular medical conditions. Diabetic retinopathy, a microvascular disease of …

Diseases affecting the posterior segment of the eye such as age-related macular
degeneration and diabetic retinopathy are leading causes of blindness all over the world …