Thrombosis is the most feared complication of cardiovascular diseases and a main cause of
death worldwide, making it a major health-care challenge. Platelets and the coagulation …

Damage-associated molecular patterns (DAMPs) are endogenous molecules which foment
inflammation and are associated with disorders in sepsis and cancer. Thus, therapeutically …

Neutrophil extracellular traps (NETs) production is a major strategy employed by
polymorphonuclear neutrophils (PMNs) to fight against microbes. NETs have been …

Neutrophil extracellular traps (NETs) have recently emerged as a newly recognized
contributor to venous and arterial thrombosis. These strands of DNA extruded by activated or …

Beyond their well-known functions in the acute phases of the immune response, neutrophils
play important roles in the various phases of tumor initiation and progression, through the …

Neutrophils produce neutrophil extracellular traps (NETs) by expelling their extracellular
chromatin embedded with citrullinated histone H3, myeloperoxidase, and other intracellular …

Clinical observations implicate a role of eosinophils in cardiovascular diseases because
markers of eosinophil activation are elevated in atherosclerosis and thrombosis. However …

Neutrophil extracellular traps (NETs) are web-like extrusions of genetic material, which are
released upon neutrophil activation. NETs consist of a chromatin substructure, onto which a …

Vascular disease is a progressive inflammatory condition fuelled by an unhealthy lifestyle of
physical inactivity, cholesterol-rich diet, and smoking. Together with endogenous factors …

Balancing cell survival and cell death is fundamental to development and homeostasis. Cell
death is regulated by multiple interconnected signaling pathways and molecular …