Basic structural modifications for improving the practical properties of BODIPY

NA Bumagina, EV Antina, AA Ksenofontov… - Coordination Chemistry …, 2022 - Elsevier
The review considers the results of research by scientists from different countries in the field
of synthesis and photophysical property study of known BODIPY. We focus on describing the …

Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy

M Gao, F Yu, C Lv, J Choo, L Chen - Chemical Society Reviews, 2017 - pubs.rsc.org
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …

Small conjugate-based theranostic agents: an encouraging approach for cancer therapy

R Kumar, WS Shin, K Sunwoo, WY Kim… - Chemical Society …, 2015 - pubs.rsc.org
The advances in genomics, proteomics, and bioinformatics have directed the development
of new anticancer agents to reduce drug abuse and increase safe and specific drug …

Self‐immolative spacers: kinetic aspects, structure–property relationships, and applications

A Alouane, R Labruère, T Le Saux… - Angewandte Chemie …, 2015 - Wiley Online Library
Self‐immolative spacers are covalent assemblies tailored to correlate the cleavage of two
chemical bonds after activation of a protective part in a precursor: Upon stimulation, the …

Azadipyrromethenes: from traditional dye chemistry to leading edge applications

Y Ge, DF O'Shea - Chemical Society Reviews, 2016 - pubs.rsc.org
Azadipyrromethenes were first described over 70 years ago as blue pigments, but now are
rapidly emerging as a compound class with highly desirable near infrared photophysical …

Disulfide-based multifunctional conjugates for targeted theranostic drug delivery

MH Lee, JL Sessler, JS Kim - Accounts of chemical research, 2015 - ACS Publications
Conspectus Theranostics, chemical entities designed to combine therapeutic effects and
imaging capability within one molecular system, have received considerable attention in …

Glutathione-mediated nanomedicines for cancer diagnosis and therapy

Y Ding, Y Dai, M Wu, L Li - Chemical Engineering Journal, 2021 - Elsevier
As one of the most important intracellular antioxidants and redox balance regulators,
glutathione (GSH) plays a vital role in cell growth and proliferation, drug detoxification and …

Fluorogenic reaction-based prodrug conjugates as targeted cancer theranostics

MH Lee, A Sharma, MJ Chang, J Lee, S Son… - Chemical Society …, 2018 - pubs.rsc.org
Theranostic systems are receiving ever-increasing attention due to their potential
therapeutic utility, imaging enhancement capability, and promise for advancing the field of …

An activatable prodrug for the treatment of metastatic tumors

EJ Kim, S Bhuniya, H Lee, HM Kim… - Journal of the …, 2014 - ACS Publications
Metastatic cancers have historically been difficult to treat. However, metastatic tumors have
been found to have high levels of reactive oxygen species such as hydrogen peroxide …

Next generation NIR fluorophores for tumor imaging and fluorescence-guided surgery: A review

A Haque, MSH Faizi, JA Rather, MS Khan - Bioorganic & medicinal …, 2017 - Elsevier
Cancer is a group of diseases responsible for the major causes of mortality and morbidity
among people of all ages. Even though medical sciences have made enormous growth …