Isavuconazole: a new broad-spectrum triazole antifungal agent
MH Miceli, CA Kauffman - Clinical Infectious Diseases, 2015 - academic.oup.com
Isavuconazole is a new extended-spectrum triazole with activity against yeasts, molds, and
dimorphic fungi. It is approved for the treatment of invasive aspergillosis and mucormycosis …
dimorphic fungi. It is approved for the treatment of invasive aspergillosis and mucormycosis …
Dermatophyte resistance to antifungal drugs: mechanisms and prospectus
Dermatophytes comprise pathogenic fungi that have a high affinity for the keratinized
structures present in nails, skin, and hair, causing superficial infections known as …
structures present in nails, skin, and hair, causing superficial infections known as …
High terbinafine resistance in Trichophyton interdigitale isolates in Delhi, India harbouring mutations in the squalene epoxidase gene
In the last few years, infections caused by dermatophytes along with a concomitant increase
in the number of difficult to treat cases have increasingly been recognised, indicating that …
in the number of difficult to treat cases have increasingly been recognised, indicating that …
Emerging Terbinafine Resistance in Trichophyton: Clinical Characteristics, Squalene Epoxidase Gene Mutations, and a Reliable EUCAST Method for Detection
DML Saunte, RK Hare, KM Jørgensen… - Antimicrobial agents …, 2019 - Am Soc Microbiol
In recent years, cases involving terbinafine-resistant Trichophyton isolates have been
reported increasingly, particularly in India. We present 14 cases of terbinafine treatment …
reported increasingly, particularly in India. We present 14 cases of terbinafine treatment …
State-of-the-art dermatophyte infections: epidemiology aspects, pathophysiology, and resistance mechanisms
The burden of fungal infections is not widely appreciated. Although these infections are
responsible for over one million deaths annually, it is estimated that one billion people are …
responsible for over one million deaths annually, it is estimated that one billion people are …
Molecular Epidemiology and Antifungal Susceptibility of Trichophyton Isolates in Greece: Emergence of Terbinafine-Resistant Trichophyton mentagrophytes Type …
M Siopi, I Efstathiou, K Theodoropoulos, S Pournaras… - Journal of Fungi, 2021 - mdpi.com
Trichophyton isolates with reduced susceptibility to antifungals are now increasingly
reported worldwide. We therefore studied the molecular epidemiology and the in vitro …
reported worldwide. We therefore studied the molecular epidemiology and the in vitro …
A unique multidrug-resistant clonal Trichophyton population distinct from Trichophyton mentagrophytes/Trichophyton interdigitale complex causing an ongoing …
There has been a considerable upsurge of extensive, treatment recalcitrant,
dermatophytosis presenting as tinea corporis and tinea cruris in India since the past few …
dermatophytosis presenting as tinea corporis and tinea cruris in India since the past few …
Multidrug‐resistant Trichophyton mentagrophytes genotype VIII in an Iranian family with generalized dermatophytosis: report of four cases and review of literature
Background The global spread of terbinafine‐resistant Trichophyton mentagrophytes with
point mutations in the squalene epoxidase (SQLE) gene is a big concern. Aim The present …
point mutations in the squalene epoxidase (SQLE) gene is a big concern. Aim The present …
The Emerging Terbinafine-Resistant Trichophyton Epidemic: What Is the Role of Antifungal Susceptibility Testing?
JJ Shen, MC Arendrup, S Verma, DML Saunte - Dermatology, 2022 - karger.com
Background: Dermatophytosis is commonly encountered in the dermatological clinics. The
main aetiological agents in dermatophytosis of skin and nails in humans are Trichophyton …
main aetiological agents in dermatophytosis of skin and nails in humans are Trichophyton …
Correlation of In Vitro Susceptibility Based on MICs and Squalene Epoxidase Mutations with Clinical Response to Terbinafine in Patients with Tinea Corporis/Cruris
Recalcitrant dermatophytoses are on the rise in India. High MICs of terbinafine (TRB) and
squalene epoxidase (SQLE) gene mutations conferring resistance in Trichophyton spp …
squalene epoxidase (SQLE) gene mutations conferring resistance in Trichophyton spp …