The cytoskeleton—a complex interacting meshwork

T Hohmann, F Dehghani - Cells, 2019 - mdpi.com
The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

Roles of the actin cytoskeleton in aging and age-associated diseases

WF Lai, WT Wong - Ageing research reviews, 2020 - Elsevier
The integrity of the cytoskeleton is essential to diverse cellular processes such as
phagocytosis and intracellular trafficking. Disruption of the organization and dynamics of the …

Giant viruses encode actin-related proteins

V Da Cunha, M Gaia, H Ogata, O Jaillon… - Molecular biology …, 2022 - academic.oup.com
The emergence of the eukaryotic cytoskeleton is a critical yet puzzling step of
eukaryogenesis. Actin and actin-related proteins (ARPs) are ubiquitous components of this …

[HTML][HTML] Dynamizing nuclear actin filaments

M Plessner, R Grosse - Current opinion in cell biology, 2019 - Elsevier
While it is long known that actin is part of the nuclear proteome, its properties and functions
as regulated, functional and dynamically assembled actin filaments are only recently …

Actin cytoskeleton in angiogenesis

N Yadunandanan Nair, V Samuel, L Ramesh… - Biology …, 2022 - journals.biologists.com
Actin, one of the most abundant intracellular proteins in mammalian cells, is a critical
regulator of cell shape and polarity, migration, cell division, and transcriptional response …

GTPases, genome, actin: A hidden story in DNA damage response and repair mechanisms

YT Magalhaes, JO Farias, LE Silva, FL Forti - DNA repair, 2021 - Elsevier
Abstract The classical small Rho GTPase (Rho, Rac, and Cdc42) protein family is mainly
responsible for regulating cell motility and polarity, membrane trafficking, cell cycle control …

Diversity and evolution of actin-dependent phenotypes

KB Velle, LK Fritz-Laylin - Current opinion in genetics & development, 2019 - Elsevier
The actin cytoskeleton governs a vast array of core eukaryotic phenotypes that include cell
movement, endocytosis, vesicular trafficking, and cytokinesis. Although the basic principle …

Phylogenic determinants of cardiovascular frailty, focus on hemodynamics and arterial smooth muscle cells

JB Michel - Physiological reviews, 2020 - journals.physiology.org
The evolution of the circulatory system from invertebrates to mammals has involved the
passage from an open system to a closed in-parallel system via a closed in-series system …

Parallel import mechanisms ensure the robust nuclear localization of actin in Drosophila

P Borkúti, I Kristó, A Szabó, C Bajusz… - Frontiers in Molecular …, 2022 - frontiersin.org
Actin, as an ancient and fundamental protein, participates in various cytoplasmic as well as
nuclear functions in eukaryotic cells. Based on its manifold tasks in the nucleus, it is a …

Giant viruses encode novel types of actins possibly related to the origin of eukaryotic actin: the viractins

VD Cunha, M Gaia, H Ogata, O Jaillon, TO Delmont… - BioRxiv, 2020 - biorxiv.org
Actin is a major component of the eukaryotic cytoskeleton. Many related actin homologues
can be found in eukaryotes1, some of them being present in most or all eukaryotic lineages …