Intervertebral disc (IVD) degeneration (IDD) is a common disorder that affects the spine and
is a major cause of lower back pain (LBP). The extracellular matrix (ECM) is the structural …

The intervertebral disc is not isolated from other tissues. Recently, abundant research has
linked intervertebral disc homeostasis and degeneration to various systemic diseases …

Background The relationship between osteoporosis and intervertebral disc (IVD)
degeneration remains controversial. Novel quantitative Dixon (Q‐Dixon) and GRAPPATINI …

Intervertebral disc degeneration (IVDD) has been a complex disorder resulted from genetic
and environmental risk factors. The aim of this study was to identify the risk factors …

Background: Intervertebral disc degenerative diseases is one the main causes of lumbago,
and its main pathological mechanism is intervertebral disc degeneration (IDD). As shown in …

Abstract The Biospecimen Collection and Processing Working Group of the National
Institutes of Health (NIH) HEAL Initiative BACPAC Research Program was charged with …

The Waveflex semi-rigid-dynamic-internal-fixation system shows good short-term effects in
the treatment of lumbar degenerative diseases, but there are few long-term follow-up …

Objectives To unravel the heterogeneity and function of microenvironmental neutrophils
during intervertebral disc degeneration (IDD). Methods Single-cell RNA sequencing (scRNA …

Diagnostic ambiguity is prevalent in medicine, and may lead to undesirable medical
consequences. In this paper, diagnostic ambiguity for lumber disc degeneration (LDD) is …

Background Lumbar disc degeneration (LDD) is a ubiquitous finding in low back pain. Many
different etiology factors may explain the LDD process, such as bone morphogenetic …