Neurodevelopmental programming—the implementation of the genetic and epigenetic
blueprints that guide and coordinate normal brain development—requires tight regulation of …

Extremely preterm babies are at increased risk of less than optimal neurodevelopment
compared with their term-born counterparts. Optimising nutrition is a promising avenue to …

Maternal obesity during pregnancy increases the risk of obesity in the offspring. Obesity,
arising from an imbalance of energy intake and expenditure, can be driven by the ingestion …

DNA methylation is an epigenetic mark involved in regulating genome function and is critical
for normal development in mammals. It has been observed that the developmental …

Rationale The birth of neurons, their migration to appropriate positions in the brain, and their
establishment of the proper synaptic contacts happen predominately during the prenatal …

The prefrontal cortex (PFC) is implicated in a variety of cognitive and executive functions and
is composed of several distinct networks, including anterior cingulate cortex (ACC), medial …

J. Neurochem.(2012) 120, 891–898. Abstract Chronic intake of high‐fat (HF) diet is known to
alter brain neurotransmitter systems that participate in the central regulation of food intake …

Opioid system dysregulation has been observed in both genetic and high-fat diet (HFD)-
induced models of obesity. An understanding of the molecular mechanisms of MOR …

Transmission of epigenetic information between generations occurs in nematodes, flies and
plants, mediated by specialised small RNA pathways, modified histones and DNA …

Attention deficit/hyperactivity disorder (ADHD) is a common and highly heritable psychiatric
disorder. In addition, early life environmental factors contribute to the occurrence of ADHD …