Decidualization denotes the transformation of endometrial stromal fibroblasts into
specialized secretory decidual cells that provide a nutritive and immunoprivileged matrix …

BACKGROUND Obesity has now been recognized as a high-risk factor for reproductive
health. Although remarkable advancements have been made in ART, a considerable …

Uterine receptivity to implantation varies among species, and involves changes in
expression of genes that are coordinate with attachment of trophectoderm to uterine lumenal …

The moniker lysophospholipid incorporates two broad families of membrane-derived lipids:
the glycerophospholipids and the sphingolipids. 1 Primary representatives of these two arms …

Metabolic regulation plays important roles in embryo development and uterine receptivity
during early pregnancy, ultimately influencing pregnancy efficiency in mammals. The …

The loss of endothelial connective integrity and endothelial barrier dysfunction can lead to
increased vascular injury, which is related to the activation of endothelial inflammasomes …

Uterine decidualization, a process that occurs in response to embryo implantation, is critical
for embryonic survival and thus is a key event for successful pregnancy. Here we show that …

BACKGROUND Lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) are two
prominent signaling lysophospholipids (LPs) exerting their functions through a group of G …

Abstract Sphingosine-1-phosphate (S1P) is now recognized as a lipid mediator that acts via
G-protein-coupled receptors. S1P receptors couple to various heterotrimeric G-proteins and …

Many essential elements exist in nature with significant influence on human health.
Angiogenesis is vital in developmental, repair, and regenerative processes, and its aberrant …