Postoperative antibiotics for complicated appendicitis in children: piperacillin/tazobactam versus ceftriaxone with metronidazole

S Zeineddin, JB Pitt, S Linton, C De Boer, A Hu… - Journal of pediatric …, 2023 - Elsevier
Introduction Recent studies are discordant regarding postoperative use of piperacillin/
tazobactam (PT) versus ceftriaxone/metronidazole (CM) for pediatric complicated …

IMPPACT (Intravenous Monotherapy for Postoperative Perforated Appendicitis in Children Trial): randomized clinical trial of monotherapy versus multi-drug antibiotic …

J Lee, EM Garvey, N Bundrant… - Annals of …, 2021 - journals.lww.com
Background: Perforated appendicitis is the most common cause of intraabdominal abscess
(IAA) in children. The optimal postoperative antibiotic regimen to reduce IAA has evolved in …

Optimizing antibiotic management for patients with acute appendicitis: A quality improvement study

J Beckermann, ME Linnaus, H Swartz, S Stewart… - Surgery, 2024 - Elsevier
Background To decrease surgical site infections after appendectomy for acute appendicitis,
preoperative broad-spectrum antibiotics are often used in clinical practice. However, this …

Perioperative Antibiotics in Appendicitis—Do We Need to Adjust Therapy for the Elderly? A Matched Pair Analysis

J Strohäker, M Brüschke, N Leser, A Königsrainer… - Antibiotics, 2022 - mdpi.com
(1) Background: Perioperative Antibiotics for acute complicated appendicitis are a standard
of care. While there are plenty of trials for pediatric patients, data for elderly patients are …

Intraoperative bacterial cultures fail to reliably predict the bacterial spectrum encountered during infectious complications after appendicitis

JKH Strohäker, MJ Brüschke, R Bachmann… - Updates in Surgery, 2024 - Springer
Acute appendicitis is a common surgical emergency. Complicated appendicitis usually
warrants perioperative antibiotic treatment in order to prevent infectious complications …