Narcolepsy

TE Scammell - New England Journal of Medicine, 2015 - Mass Medical Soc
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Genetic and familial aspects of narcolepsy

E Mignot - Neurology, 1998 - AAN Enterprises
Narcolepsy-cataplexy is a disabling sleep disorder characterized by excessive daytime
sleepiness and abnormal REM sleep. The development of human narcolepsy involves …

Association of lifestyle with sleep health in general population in China: a cross-sectional study

YB Zheng, YT Huang, YM Gong, MZ Li, N Zeng… - Translational …, 2024 - nature.com
The concept of a healthy lifestyle is receiving increasing attention. This study sought to
identify an optimal healthy lifestyle profile associated with sleep health in general population …

HLA DQB1* 0602 is associated with cataplexy in 509 narcoleptic patients

E Mignot, R Hayduk, J Black, FC Grumet… - Sleep, 1997 - academic.oup.com
Narcolepsy is a sleep disorder associated with HLA DR15 (DR2) and DQB1* 0602. We HLA
typed 509 patients enrolled in a clinical trial for the drug modafinil and analyzed the results …

DQB1 locus alone explains most of the risk and protection in narcolepsy with cataplexy in Europe

Sleep, 2014 - academic.oup.com
Abstract Study Objective: Prior research has identified five common genetic variants
associated with narcolepsy with cataplexy in Caucasian patients. To replicate and/or extend …

[HTML][HTML] Pharmacological aspects of human and canine narcolepsy

S Nishino, E Mignot - Progress in neurobiology, 1997 - Elsevier
Narcolepsy-cataplexy is a disabling neurological disorder that affects 1 2000 individuals.
The main clinical features of narcolepsy, excessive daytime sleepiness and symptoms of …

Narcolepsy: clinical features, new pathophysiologic insights, and future perspectives

S Overeem, E Mignot, J GertvanDijk… - Journal of Clinical …, 2001 - journals.lww.com
Narcolepsy is characterized by excessive daytime sleepinessand abnormal manifestations
of rapid eye movement sleep such as cataplexy. Theauthors review the clinical features of …

[HTML][HTML] The autoimmune basis of narcolepsy

J Mahlios, AK De la Herrán-Arita, E Mignot - Current opinion in …, 2013 - Elsevier
Highlights•Narcolepsy is caused by the loss of hypocretin-producing neurons in the
brain.•HLA DQB1* 06: 02 association suggests an autoimmune basis for narcolepsy.• …

Validation of a cataplexy questionnaire in 983 sleep-disorders patients

S Anic-Labat, C Guilleminault, HC Kraemer, J Meehan… - Sleep, 1999 - academic.oup.com
Our goal was to validate a self-administered narcolepsy questionnaire focusing on
cataplexy. Nine hundred and eighty three consecutive subjects entering the Stanford Sleep …

The neurobiology, diagnosis, and treatment of narcolepsy

TE Scammell - Annals of Neurology: Official Journal of the …, 2003 - Wiley Online Library
Narcolepsy is a common cause of chronic sleepiness distinguished by intrusions into
wakefulness of physiological aspects of rapid eye movement sleep such as cataplexy and …