Potassium channels are particularly important in determining the shape and duration of the
action potential, controlling the membrane potential, modulating hormone secretion …

In many cell types rises in cytosolic calcium, either due to influx from the extracellular space,
or by release from an intracellular store activates calcium dependent potassium currents on …

Malfunctions of potassium channels are increasingly implicated as causes of neurological
disorders. However, the functional roles of the large-conductance voltage-and Ca2+ …

Transient changes in the activity of midbrain dopamine neurons encode an error signal that
contributes to associative learning. Although considerable attention has been devoted to the …

The convulsant alkaloid bicuculline continues to be investigated more than 40 years after
the first publication of its action as an antagonist of receptors for the inhibitory …

γ-Aminobutyric acid (GABA) has been proposed to function as a paracrine signaling
molecule in islets of Langerhans. We have shown that rat β-cells release GABA by Ca2+ …

Calcium-activated potassium channels are a large family of potassium channels that are
found throughout the central nervous system and in many other cell types. These channels …

At least 70% of the afferents to substantia nigra dopaminergic neurons are GABAergic. The
vast majority of these arise from the neostriatum, the external globus pallidus and the …

The present study aimed to examine the antidepressant-like effect of the neurosteroid 3α-
hydroxy-5α-pregnan-20-one (3α, 5α THP) using the forced swim test in mice …

Virtually every neuron within the suprachiasmatic nucleus (SCN) communicates via
GABAergic signaling. The extracellular levels of GABA within the SCN are determined by a …