Does it matter what we eat for our mental health? Accumulating data suggests that this may
indeed be the case and that diet and nutrition are not only critical for human physiology and …

Motor neuron diseases (MNDs) are an etiologically heterogeneous group of disorders of
neurodegenerative origin, which result in degeneration of lower (LMNs) and/or upper motor …

Sequence-specific nucleases like TALENs and the CRISPR/Cas9 system have greatly
expanded the genome editing possibilities in model organisms such as zebrafish. Both …

Zebrafish are a unique cell to behavior model for studying the basic biology of human
inherited neurological conditions. Conserved vertebrate genetics and optical transparency …

Mutations in Kinesin proteins (Kifs) are linked to various neurological diseases, but the
specific and redundant functions of the vertebrate Kifs are incompletely understood. For …

The mutations in the genes encoding the subunits of complex I of the mitochondrial electron
transport chain are the most common cause of Leber's hereditary optic neuropathy (LHON) …

CRISPR/Cas9-mediated targeted mutagenesis allows efficient generation of loss-of-function
alleles in zebrafish. To date, this technology has been primarily used to generate genetic …

Kinesins are motor proteins involved in microtubule (MT)-mediated intracellular transport.
They contribute to key cellular processes, including intracellular trafficking, organelle …

In animals, specification of the primordial germ cells (PGCs), the stem cells of the germ line,
is required to transmit genetic information from one generation to the next. Bucky ball (Buc) …

Cargo transport by molecular motors along microtubules is essential for the function of
eukaryotic cells, in particular neurons in which axonal transport defects constitute the early …