The pain matrix is conceptualised here as a fluid system composed of several interacting
networks. A nociceptive matrix receiving spinothalamic projections (mainly posterior …

CONTEXT: The perception of pain due to an acute injury or in clinical pain states undergoes
substantial processing at supraspinal levels. Supraspinal, brain mechanisms are …

Background: Pain is a common complication after stroke and is associated with the
presence of depression, cognitive dysfunction, and impaired quality of life. It remains …

A dramatic increase in the use and dependence of prescription opioids has occurred within
the last 10 years. The consequences of long-term prescription opioid use and dependence …

Background. We assessed mirror visual feedback (MVF) to test the hypothesis that
incongruence between motor output and sensory input produces complex regional pain …

OBJECTIVE: To examine the function of the nociceptive system in patients with fibromyalgia
(FM) using functional magnetic resonance imaging (fMRI). METHODS: Two groups of …

Complex regional pain syndrome (CRPS) is the result of changes to the somatosensory
systems that process noxious, tactile, and thermal information; to the sympathetic systems …

We describe the clinical features of 103 patients presenting with fixed dystonia and report
the prospective assessment and investigation of 41 of them. Most patients were female …

Chronic pain can develop from numerous conditions and is one of the most widespread and
disabling health problems today. Unfortunately, the pathophysiology of chronic pain in most …

Complex regional pain syndromes (CRPS, formerly reflex sympathetic dystrophy and
causalgia) are neuropathic pain conditions of one extremity developing inadequately after a …