Autophagy is a core molecular pathway for the preservation of cellular and organismal
homeostasis. Pharmacological and genetic interventions impairing autophagy responses …

Duchenne muscular dystrophy (DMD) is an X-linked muscle-wasting disease caused by the
loss of dystrophin. DMD is associated with muscle degeneration, necrosis, inflammation …

Background Adipose tissue-derived adipokines are involved in various crosstalk between
adipose tissue and other organs. Omentin1, a novel adipokine, exerts vital roles in the …

Duchenne muscular dystrophy (DMD) is a severe, progressive, and ultimately fatal disease
of skeletal muscle wasting, respiratory insufficiency, and cardiomyopathy. The identification …

The serine/threonine kinase, PINK1, and the E3 ubiquitin ligase, Parkin, are known to
facilitate LC3-dependent autophagosomal encasement and lysosomal clearance of …

Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy, and despite
advances in genetic and pharmacological disease-modifying treatments, its management …

Duchenne muscular dystrophy (DMD) is a devastating disease featuring skeletal muscle
wasting, respiratory insufficiency, and cardiomyopathy. Historically, respiratory failure has …

Duchenne muscular dystrophy (DMD) is characterized by rapid wasting of skeletal muscle.
Mitochondrial dysfunction is a well-known pathological feature of DMD. However, whether …

Mitochondrial stress may be a secondary contributor to muscle weakness in inherited
muscular dystrophies. Duchenne muscular dystrophy has received the majority of attention …

Duchenne muscular dystrophy (DMD) is a devastating disease affecting approximately 1 in
every 3,500 male births worldwide. Multiple mutations in the dystrophin gene have been …