Crosstalk between the oxidative stress and glia cells after stroke: from mechanism to therapies

G Zhu, X Wang, L Chen, C Lenahan, Z Fu… - Frontiers in …, 2022 - frontiersin.org
Stroke is the second leading cause of global death and is characterized by high rates of
mortality and disability. Oxidative stress is accompanied by other pathological processes …

Iron, ferroptosis, and ischemic stroke

J Guo, Q Tuo, P Lei - Journal of Neurochemistry, 2023 - Wiley Online Library
Over 30 million people suffer from the consequences of ischemic stroke. The precise
molecular mechanism of neuronal damage during ischemic stroke remains unclear; …

Role of ferroptosis in stroke

Y Xu, K Li, Y Zhao, L Zhou, Y Liu, J Zhao - Cellular and Molecular …, 2023 - Springer
Stroke is a common and serious nervous system disease caused by the rupture or blockage
of the cardiovascular system. It causes millions of deaths and disabilities every year, which …

Iron homeostasis and ferroptosis in human diseases: mechanisms and therapeutic prospects

Q Ru, Y Li, L Chen, Y Wu, J Min, F Wang - Signal transduction and …, 2024 - nature.com
Iron, an essential mineral in the body, is involved in numerous physiological processes,
making the maintenance of iron homeostasis crucial for overall health. Both iron overload …

Iron homeostasis imbalance and ferroptosis in brain diseases

H Long, W Zhu, L Wei, J Zhao - MedComm, 2023 - Wiley Online Library
Brain iron homeostasis is maintained through the normal function of blood–brain barrier and
iron regulation at the systemic and cellular levels, which is fundamental to normal brain …

Mechanism of ferroptosis and its relationships with other types of programmed cell death: insights for potential therapeutic benefits in traumatic brain injury

Q Pang, L Zheng, Z Ren, H Xu, H Guo… - Oxidative Medicine …, 2022 - Wiley Online Library
Traumatic brain injury (TBI) is a serious health issue with a high incidence, high morbidity,
and high mortality that poses a large burden on society. Further understanding of the …

Research progress on perioperative blood-brain barrier damage and its potential mechanism

Y Qiu, C Mo, S Xu, L Chen, W Ye, Y Kang… - Frontiers in Cell and …, 2023 - frontiersin.org
The blood-brain barrier (BBB) is an important barrier separating the central nervous system
from the periphery. The composition includes endothelial cells, pericytes, astrocytes …

Based Analytical Devices for Accurate Assessment of Transferrin Saturation in Diagnosed Clinical Samples from Ischemic Stroke Patients

S Dortez, N DeGregorio-Rocasolano, M Millán… - Analytical …, 2023 - ACS Publications
For the first time, a paper-based analytical device (PAD) was developed for the assessment
of transferrin saturation (TSAT), which is defined as the ratio between iron bound to …

Ferroptosis and endoplasmic reticulum stress in ischemic stroke

Y Li, M Li, S Feng, Q Xu, X Zhang… - Neural Regeneration …, 2023 - journals.lww.com
Ferroptosis is a form of non-apoptotic programmed cell death, and its mechanisms mainly
involve the accumulation of lipid peroxides, imbalance in the amino acid antioxidant system …

Potential intervention target of atherosclerosis: Ferroptosis

J Li, L Xu, YX Zuo, XQ Chang… - Molecular Medicine …, 2022 - spandidos-publications.com
Atherosclerosis (AS) is a chronic inflammatory disease of the blood vessels, which is mainly
characterized by the form of atherosclerotic plaques and vascular endothelial injury. Its …