Simple Summary This review aims to shed light on the proliferative markers important in the
everyday clinical management of colorectal cancer (CRC), ranging from simple methods of …

Results: Cyclin D1 over-expression was absent in normal mucosa, while 15% cases of
adenoma showed its over-expression. In CRC, Cyclin D1 was expressed at high levels in …

Background/Aim: Cyclins D1 and E play different roles in the cell cycle. Cyclin E promotes
chromosome instability, whereas cyclin D1 regulates apoptosis of cells. This study evaluated …

Purpose: Despite many known risk factors for the colorectal cancer (CRC) recurrence,
significant differences in diseasefree survival (DFS) impose the need to look for new …

Background Cyclin D1 is an essential part of oncogenic transformation. We previously
proved that cyclin D1 was upregulated in nasopharyngeal carcinoma (NPC) and promoted …

Background: Cancer is one of the biggest health problems in the world. Colon
adenocarcinoma is the third most common cancer and is the fourth most common cause of …

细胞周期蛋白D1 (CCND1) 在细胞周期调节作用获得公认, CCND1 的异常表达与癌症的发展,
预后的关联受到越来越多的重视. 笔者选取了临床上常见的乳腺癌, 结直肠癌, 食管癌 …

Background: This study was conducted to evaluate the expression of Cyclin D1 in colorectal
carcinoma, and to correlate Cyclin D1 positivity with the grade of the tumor along with other …

Background: Colorectal cancer (CRC) is known to be the third most frequently diagnosed
cancer and the fourth leading cause of cancer death worldwide. In Egypt, colorectal …

Background Colorectal cancer (CRC) is one of the most frequent cancers worldwide. Cyclin
D1 (CNND1) and cyclooxygenase-2 (Cox-2) are expressed in a plethora of neoplastic …