Ammonia borane NH3· BH3 is considered a promising material for hydrogen storage and
release, and is attracting increasing attention as a relatively inexpensive, atom economy …

Fast screening of enzyme variants is crucial for tailoring biocatalysts for the asymmetric
synthesis of non-natural chiral chemicals, such as amines. However, most existing …

Biocatalysis provides a potentially sustainable means of chemical manufacturing. However,
the tailoring of enzymes to industrial processes is often laborious and time consuming …

Monoamine oxidases (MAO) are biocatalysts for the oxidation of a wide range of different
amines including α-chiral amines. Their high selectivity and activity, along with the …

A new directed evolution approach is presented to enhance the activity of an enzyme and to
manipulate stereoselectivity by focusing iterative saturation mutagenesis (ISM) …

In recent years the usefulness of enzymatic systems to obtain a single stereoisomerically
pure compound starting from a racemate has been expanded. Moreover, current advances …

A novel amine oxidase (AO)/imine reductase (IRED) system was developed for the
deracemization of racemic amines. By combining (R)‐6‐hydroxy‐d‐nicotine oxidase (6 …

The deracemization of racemic amines to yield enantioenriched amines using S‐
stereoselective amine oxidases (AOx) has recently been attracting attention. However, R …

Promiscuous enzymes can be recruited to serve new functions when a genetic or
environmental change makes catalysis of a novel reaction important for fitness or even …

The power of complementary chemocatalytic and biocatalytic transformations is
demonstrated in the asymmetric synthesis of 2-substituted tetrahydroquinolines. A series of …